Determinants of prognosis and management of patients with pulmonary hypertension due to left heart disease: a systematic review
Patients with pulmonary hypertension (PH) associated with left heart disease usually have a complex comorbidity status and a postcapillary component of PH. The presence and identification of a combined post-/precapillary PH in a cohort of patients with left heart disease is reflected in the more pro...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2023-03-01
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| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/5115 |
| _version_ | 1797856549094293504 |
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| author | I. N. Lyapina Yu. E. Teplova T. V. Martynyuk |
| author_facet | I. N. Lyapina Yu. E. Teplova T. V. Martynyuk |
| author_sort | I. N. Lyapina |
| collection | DOAJ |
| description | Patients with pulmonary hypertension (PH) associated with left heart disease usually have a complex comorbidity status and a postcapillary component of PH. The presence and identification of a combined post-/precapillary PH in a cohort of patients with left heart disease is reflected in the more pronounced structural and functional right ventricular changes due to higher pulmonary vascular resistance. Patients with combined post-/ precapillary PH have reduced exercise tolerance and PH phenotype similar to pulmonary arterial hypertension. Detection of combined PH is critical as it may influence the prognosis and management of patients. This review presents modern prognosis markers for patients with PH due to left heart disease, which can be used in clinical practice. The results of randomized clinical trials and pilot studies on the expansion of treatment options in group 2 patients, including the use of PAH-specific agents, were analyzed. The prospects for the treatment of this cohort of patients are discussed. |
| first_indexed | 2024-04-09T20:42:19Z |
| format | Article |
| id | doaj.art-5e1c3f6741424167b0873e918df4fffb |
| institution | Directory Open Access Journal |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| last_indexed | 2024-04-09T20:42:19Z |
| publishDate | 2023-03-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj.art-5e1c3f6741424167b0873e918df4fffb2023-03-29T21:23:43Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202023-03-01281S10.15829/1560-4071-2023-51153755Determinants of prognosis and management of patients with pulmonary hypertension due to left heart disease: a systematic reviewI. N. Lyapina0Yu. E. Teplova1T. V. Martynyuk2Research Institute for Complex Issues of Cardiovascular DiseasesResearch Institute for Complex Issues of Cardiovascular DiseasesE. I. Chazov National Medical Research Center of CardiologyPatients with pulmonary hypertension (PH) associated with left heart disease usually have a complex comorbidity status and a postcapillary component of PH. The presence and identification of a combined post-/precapillary PH in a cohort of patients with left heart disease is reflected in the more pronounced structural and functional right ventricular changes due to higher pulmonary vascular resistance. Patients with combined post-/ precapillary PH have reduced exercise tolerance and PH phenotype similar to pulmonary arterial hypertension. Detection of combined PH is critical as it may influence the prognosis and management of patients. This review presents modern prognosis markers for patients with PH due to left heart disease, which can be used in clinical practice. The results of randomized clinical trials and pilot studies on the expansion of treatment options in group 2 patients, including the use of PAH-specific agents, were analyzed. The prospects for the treatment of this cohort of patients are discussed.https://russjcardiol.elpub.ru/jour/article/view/5115pulmonary hypertension due to left heart diseasecombined post-/ precapillary pulmonary hypertensionprognostic markerstreatment prospects |
| spellingShingle | I. N. Lyapina Yu. E. Teplova T. V. Martynyuk Determinants of prognosis and management of patients with pulmonary hypertension due to left heart disease: a systematic review Российский кардиологический журнал pulmonary hypertension due to left heart disease combined post-/ precapillary pulmonary hypertension prognostic markers treatment prospects |
| title | Determinants of prognosis and management of patients with pulmonary hypertension due to left heart disease: a systematic review |
| title_full | Determinants of prognosis and management of patients with pulmonary hypertension due to left heart disease: a systematic review |
| title_fullStr | Determinants of prognosis and management of patients with pulmonary hypertension due to left heart disease: a systematic review |
| title_full_unstemmed | Determinants of prognosis and management of patients with pulmonary hypertension due to left heart disease: a systematic review |
| title_short | Determinants of prognosis and management of patients with pulmonary hypertension due to left heart disease: a systematic review |
| title_sort | determinants of prognosis and management of patients with pulmonary hypertension due to left heart disease a systematic review |
| topic | pulmonary hypertension due to left heart disease combined post-/ precapillary pulmonary hypertension prognostic markers treatment prospects |
| url | https://russjcardiol.elpub.ru/jour/article/view/5115 |
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