Progressive nicotine poisoning by multiple transdermal nicotine patches

The pharmacokinetic properties of transdermal nicotine patches (TNPs) are different from those of other routes of nicotine administration; further, acute nicotine poisoning by TNPs may present with different clinical features. In the present report, we describe the case of a 23-year-old woman who wa...

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Main Authors: Jeong Ho Kang, Sung Kgun Lee
Format: Article
Language:English
Published: Institute for Medical Science, Jeju National University 2021-08-01
Series:Journal of Medicine and Life Science
Subjects:
Online Access:http://www.e-jmls.org/upload/pdf/jmls-2021-18-2-31.pdf
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author Jeong Ho Kang
Sung Kgun Lee
author_facet Jeong Ho Kang
Sung Kgun Lee
author_sort Jeong Ho Kang
collection DOAJ
description The pharmacokinetic properties of transdermal nicotine patches (TNPs) are different from those of other routes of nicotine administration; further, acute nicotine poisoning by TNPs may present with different clinical features. In the present report, we describe the case of a 23-year-old woman who was admitted to emergency department (ED) at Jeju National University Hospital with loss of consciousness. Five hours before the ED visit, she used multiple TNPs to attempt suicide. Initially, nausea and vomiting occurred, and the symptoms worsened over time. We immediately removed the TNPs, and the application sites were gently washed with sterile water. The patient’s level of consciousness gradually improved, and she fully recovered an altered mental status 5 hours later. Her initial urinary cotinine level was 324 ng/mL. Physicians should be aware that acute nicotine poisoning by TNPs can cause various toxic symptoms.
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spelling doaj.art-5e1d1af0e58f49e8aab1d134832611e82023-08-31T05:21:28ZengInstitute for Medical Science, Jeju National UniversityJournal of Medicine and Life Science2671-49222021-08-01182313410.22730/jmls.2021.18.2.31217Progressive nicotine poisoning by multiple transdermal nicotine patchesJeong Ho Kang0Sung Kgun Lee1 Department of Emergency Medicine, Jeju National University College of Medicine, Jeju, Republic of Korea Department of Emergency Medicine, Jeju National University Hospital, Jeju, Republic of KoreaThe pharmacokinetic properties of transdermal nicotine patches (TNPs) are different from those of other routes of nicotine administration; further, acute nicotine poisoning by TNPs may present with different clinical features. In the present report, we describe the case of a 23-year-old woman who was admitted to emergency department (ED) at Jeju National University Hospital with loss of consciousness. Five hours before the ED visit, she used multiple TNPs to attempt suicide. Initially, nausea and vomiting occurred, and the symptoms worsened over time. We immediately removed the TNPs, and the application sites were gently washed with sterile water. The patient’s level of consciousness gradually improved, and she fully recovered an altered mental status 5 hours later. Her initial urinary cotinine level was 324 ng/mL. Physicians should be aware that acute nicotine poisoning by TNPs can cause various toxic symptoms.http://www.e-jmls.org/upload/pdf/jmls-2021-18-2-31.pdfnicotinetransdermal patchsuicide
spellingShingle Jeong Ho Kang
Sung Kgun Lee
Progressive nicotine poisoning by multiple transdermal nicotine patches
Journal of Medicine and Life Science
nicotine
transdermal patch
suicide
title Progressive nicotine poisoning by multiple transdermal nicotine patches
title_full Progressive nicotine poisoning by multiple transdermal nicotine patches
title_fullStr Progressive nicotine poisoning by multiple transdermal nicotine patches
title_full_unstemmed Progressive nicotine poisoning by multiple transdermal nicotine patches
title_short Progressive nicotine poisoning by multiple transdermal nicotine patches
title_sort progressive nicotine poisoning by multiple transdermal nicotine patches
topic nicotine
transdermal patch
suicide
url http://www.e-jmls.org/upload/pdf/jmls-2021-18-2-31.pdf
work_keys_str_mv AT jeonghokang progressivenicotinepoisoningbymultipletransdermalnicotinepatches
AT sungkgunlee progressivenicotinepoisoningbymultipletransdermalnicotinepatches