Cost-effective fabrication, antibacterial application and cell viability studies of modified nonwoven cotton fabric
Abstract In the present work, nonwoven cotton fabric was modified for antibacterial applications using low-cost and eco-friendly precursors. The treatment of fabric with alkali leads to the formation of active sites for surface modification, followed by dip coating with silver nanoparticles and chit...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-02-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-06391-5 |
| _version_ | 1818298142638997504 |
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| author | Rahat Nawaz Sayed Tayyab Raza Naqvi Batool Fatima Nazia Zulfiqar Muhammad Umer Farooq Muhammad Najam ul Haq Dilshad Hussain Asghar Javeed Azhar Rasul Laila Jafri Saadat Majeed Waheed Qamar Khan |
| author_facet | Rahat Nawaz Sayed Tayyab Raza Naqvi Batool Fatima Nazia Zulfiqar Muhammad Umer Farooq Muhammad Najam ul Haq Dilshad Hussain Asghar Javeed Azhar Rasul Laila Jafri Saadat Majeed Waheed Qamar Khan |
| author_sort | Rahat Nawaz |
| collection | DOAJ |
| description | Abstract In the present work, nonwoven cotton fabric was modified for antibacterial applications using low-cost and eco-friendly precursors. The treatment of fabric with alkali leads to the formation of active sites for surface modification, followed by dip coating with silver nanoparticles and chitosan. The surface was chlorinated in the next step to transform amide (N–H) groups in chitosan into N-halamine (N-Cl). The modified and unmodified surfaces of the nonwoven cotton fabric have been characterized by FTIR, SEM, and XRD. The active chlorine loading is measured with iodine/sodium thiosulphate. The antimicrobial activity and cell toxicity assay were carried out with and without modifications of nonwoven cotton fabric. The antimicrobial efficacies of loaded fabric were evaluated against four bacterial species (Micrococcus luteus, Staphylococcus aureus, Enterobacter aerogenes, and E.coli). It was found that modified fabric exhibited superior efficiency against gram-positive and gram-negative bacterial strains as compared to their bulk counterparts upon exposure without affecting strength and integrity of fabric. The overall process is economical for commercial purposes. The modified fabric can be used for antimicrobial, health, and food packaging industries, and in other biomedical applications. |
| first_indexed | 2024-12-13T04:30:38Z |
| format | Article |
| id | doaj.art-5e1dc1e4dad941a99e4e70470403f0bf |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-13T04:30:38Z |
| publishDate | 2022-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-5e1dc1e4dad941a99e4e70470403f0bf2022-12-21T23:59:33ZengNature PortfolioScientific Reports2045-23222022-02-0112111210.1038/s41598-022-06391-5Cost-effective fabrication, antibacterial application and cell viability studies of modified nonwoven cotton fabricRahat Nawaz0Sayed Tayyab Raza Naqvi1Batool Fatima2Nazia Zulfiqar3Muhammad Umer Farooq4Muhammad Najam ul Haq5Dilshad Hussain6Asghar Javeed7Azhar Rasul8Laila Jafri9Saadat Majeed10Waheed Qamar Khan11Division of Analytical Chemistry, Institute of Chemical Sciences, Bahauddin Zakariya UniversityDivision of Analytical Chemistry, Institute of Chemical Sciences, Bahauddin Zakariya UniversityDepartment of Biochemistry, Bahauddin Zakariya UniversityDivision of Analytical Chemistry, Institute of Chemical Sciences, Bahauddin Zakariya UniversityDivision of Analytical Chemistry, Institute of Chemical Sciences, Bahauddin Zakariya UniversityDivision of Analytical Chemistry, Institute of Chemical Sciences, Bahauddin Zakariya UniversityInstitute of Advanced Materials, Bahauddin Zakariya UniversityInternational Centre for Chemical and Biological Sciences, HEJ Research Institute of Chemistry, University of KarachiDepartment of Zoology, Govt. College University FaisalabadDepartment of Life Sciences, Abasyn UniversityDivision of Analytical Chemistry, Institute of Chemical Sciences, Bahauddin Zakariya UniversityDepartment of Pathology, Nishtar Medical UniversityAbstract In the present work, nonwoven cotton fabric was modified for antibacterial applications using low-cost and eco-friendly precursors. The treatment of fabric with alkali leads to the formation of active sites for surface modification, followed by dip coating with silver nanoparticles and chitosan. The surface was chlorinated in the next step to transform amide (N–H) groups in chitosan into N-halamine (N-Cl). The modified and unmodified surfaces of the nonwoven cotton fabric have been characterized by FTIR, SEM, and XRD. The active chlorine loading is measured with iodine/sodium thiosulphate. The antimicrobial activity and cell toxicity assay were carried out with and without modifications of nonwoven cotton fabric. The antimicrobial efficacies of loaded fabric were evaluated against four bacterial species (Micrococcus luteus, Staphylococcus aureus, Enterobacter aerogenes, and E.coli). It was found that modified fabric exhibited superior efficiency against gram-positive and gram-negative bacterial strains as compared to their bulk counterparts upon exposure without affecting strength and integrity of fabric. The overall process is economical for commercial purposes. The modified fabric can be used for antimicrobial, health, and food packaging industries, and in other biomedical applications.https://doi.org/10.1038/s41598-022-06391-5 |
| spellingShingle | Rahat Nawaz Sayed Tayyab Raza Naqvi Batool Fatima Nazia Zulfiqar Muhammad Umer Farooq Muhammad Najam ul Haq Dilshad Hussain Asghar Javeed Azhar Rasul Laila Jafri Saadat Majeed Waheed Qamar Khan Cost-effective fabrication, antibacterial application and cell viability studies of modified nonwoven cotton fabric Scientific Reports |
| title | Cost-effective fabrication, antibacterial application and cell viability studies of modified nonwoven cotton fabric |
| title_full | Cost-effective fabrication, antibacterial application and cell viability studies of modified nonwoven cotton fabric |
| title_fullStr | Cost-effective fabrication, antibacterial application and cell viability studies of modified nonwoven cotton fabric |
| title_full_unstemmed | Cost-effective fabrication, antibacterial application and cell viability studies of modified nonwoven cotton fabric |
| title_short | Cost-effective fabrication, antibacterial application and cell viability studies of modified nonwoven cotton fabric |
| title_sort | cost effective fabrication antibacterial application and cell viability studies of modified nonwoven cotton fabric |
| url | https://doi.org/10.1038/s41598-022-06391-5 |
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