Disseminated mucormycosis in a paediatric patient: Lictheimia corymbifera successfully treated with combination antifungal therapy
Mucormycosis is a severe fungal infection that largely affects immunocompromised individuals. It carries a high morbidity and mortality rate and is characterised by extensive angioinvasion and necrosis of host tissue. This case report details success in treating disseminated mucormycosis in a paedia...
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| Format: | Article |
| Language: | English |
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Elsevier
2014-10-01
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| Series: | Medical Mycology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211753914000359 |
| _version_ | 1818509273289719808 |
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| author | Anita Campbell Celia Cooper Stephen Davis |
| author_facet | Anita Campbell Celia Cooper Stephen Davis |
| author_sort | Anita Campbell |
| collection | DOAJ |
| description | Mucormycosis is a severe fungal infection that largely affects immunocompromised individuals. It carries a high morbidity and mortality rate and is characterised by extensive angioinvasion and necrosis of host tissue. This case report details success in treating disseminated mucormycosis in a paediatric patient with an underlying haematological malignancy. Treatment included institution of combination antifungal therapy with liposomal amphotericin B and caspofungin, aggressive surgical debridement of infected tissue and reversal of underlying immunosuppression. |
| first_indexed | 2024-12-10T22:43:21Z |
| format | Article |
| id | doaj.art-5e1eb4262b9a43a1ac0b15e826e158ae |
| institution | Directory Open Access Journal |
| issn | 2211-7539 |
| language | English |
| last_indexed | 2024-12-10T22:43:21Z |
| publishDate | 2014-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Medical Mycology Case Reports |
| spelling | doaj.art-5e1eb4262b9a43a1ac0b15e826e158ae2022-12-22T01:30:39ZengElsevierMedical Mycology Case Reports2211-75392014-10-016C182110.1016/j.mmcr.2014.08.002Disseminated mucormycosis in a paediatric patient: Lictheimia corymbifera successfully treated with combination antifungal therapyAnita CampbellCelia CooperStephen DavisMucormycosis is a severe fungal infection that largely affects immunocompromised individuals. It carries a high morbidity and mortality rate and is characterised by extensive angioinvasion and necrosis of host tissue. This case report details success in treating disseminated mucormycosis in a paediatric patient with an underlying haematological malignancy. Treatment included institution of combination antifungal therapy with liposomal amphotericin B and caspofungin, aggressive surgical debridement of infected tissue and reversal of underlying immunosuppression.http://www.sciencedirect.com/science/article/pii/S2211753914000359MucormycosisLichthemia CorymbiferaCombination antifungal therapyNeutropenia |
| spellingShingle | Anita Campbell Celia Cooper Stephen Davis Disseminated mucormycosis in a paediatric patient: Lictheimia corymbifera successfully treated with combination antifungal therapy Medical Mycology Case Reports Mucormycosis Lichthemia Corymbifera Combination antifungal therapy Neutropenia |
| title | Disseminated mucormycosis in a paediatric patient: Lictheimia corymbifera successfully treated with combination antifungal therapy |
| title_full | Disseminated mucormycosis in a paediatric patient: Lictheimia corymbifera successfully treated with combination antifungal therapy |
| title_fullStr | Disseminated mucormycosis in a paediatric patient: Lictheimia corymbifera successfully treated with combination antifungal therapy |
| title_full_unstemmed | Disseminated mucormycosis in a paediatric patient: Lictheimia corymbifera successfully treated with combination antifungal therapy |
| title_short | Disseminated mucormycosis in a paediatric patient: Lictheimia corymbifera successfully treated with combination antifungal therapy |
| title_sort | disseminated mucormycosis in a paediatric patient lictheimia corymbifera successfully treated with combination antifungal therapy |
| topic | Mucormycosis Lichthemia Corymbifera Combination antifungal therapy Neutropenia |
| url | http://www.sciencedirect.com/science/article/pii/S2211753914000359 |
| work_keys_str_mv | AT anitacampbell disseminatedmucormycosisinapaediatricpatientlictheimiacorymbiferasuccessfullytreatedwithcombinationantifungaltherapy AT celiacooper disseminatedmucormycosisinapaediatricpatientlictheimiacorymbiferasuccessfullytreatedwithcombinationantifungaltherapy AT stephendavis disseminatedmucormycosisinapaediatricpatientlictheimiacorymbiferasuccessfullytreatedwithcombinationantifungaltherapy |