Unusual location of fibrous plaque in Indonesian child with tuberosclerosis complex
Tuberosclerosis complex (TSC) is one of the most frequent genetic causes of epilepsy. A 3-year-old boy was reffered to Soetomo Hospital, Surabaya, Indonesia with chief complain of intractable seizures. The seizures were frequent and various in type. The skin present red dome shaped papules on face a...
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| Format: | Article |
| Language: | English |
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The Pan African Medical Journal
2017-09-01
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| Series: | The Pan African Medical Journal |
| Subjects: | |
| Online Access: |
https://www.panafrican-med-journal.com/content/article/28/92/pdf/92.pdf
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| _version_ | 1818916619392385024 |
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| author | Prastiya Indra Gunawan Darto Saharso |
| author_facet | Prastiya Indra Gunawan Darto Saharso |
| author_sort | Prastiya Indra Gunawan |
| collection | DOAJ |
| description | Tuberosclerosis complex (TSC) is one of the most frequent genetic causes of epilepsy. A 3-year-old boy was reffered to Soetomo Hospital, Surabaya, Indonesia with chief complain of intractable seizures. The seizures were frequent and various in type. The skin present red dome shaped papules on face and smooth, firm, nodular or fleshy lesions referred to fibrous plaque on gum, right tarsal and right hallux region. Tarsal and hallux region were unusual skin collagenous fibroma area found in TSC. Five white macules with diameter 4-5mm were also found on the trunk. Electroencephalography resulted epileptiform discharges originating from left temporal posterior and right temporal. Head MRI showed multiple tubers at bilateral cortical-subortical fronto-temporo-parieto-occipital. The patient was diagnosed as tuberous sclerosis and received 3 types of anti epileptic seizure drugs (levetiracetam, carbamazepine and vigabatrin). The treatment resulted decrease of seizure frequency. |
| first_indexed | 2024-12-20T00:21:03Z |
| format | Article |
| id | doaj.art-5e24126995d64d90aa50dea950d15124 |
| institution | Directory Open Access Journal |
| issn | 1937-8688 1937-8688 |
| language | English |
| last_indexed | 2024-12-20T00:21:03Z |
| publishDate | 2017-09-01 |
| publisher | The Pan African Medical Journal |
| record_format | Article |
| series | The Pan African Medical Journal |
| spelling | doaj.art-5e24126995d64d90aa50dea950d151242022-12-21T20:00:11ZengThe Pan African Medical JournalThe Pan African Medical Journal1937-86881937-86882017-09-01289210.11604/pamj.2017.28.92.1265212652Unusual location of fibrous plaque in Indonesian child with tuberosclerosis complexPrastiya Indra Gunawan0Darto Saharso1 Department of Child Health, Airlangga University, Soetomo Hospital, Surabaya, Indonesia Department of Child Health, Airlangga University, Soetomo Hospital, Surabaya, Indonesia Tuberosclerosis complex (TSC) is one of the most frequent genetic causes of epilepsy. A 3-year-old boy was reffered to Soetomo Hospital, Surabaya, Indonesia with chief complain of intractable seizures. The seizures were frequent and various in type. The skin present red dome shaped papules on face and smooth, firm, nodular or fleshy lesions referred to fibrous plaque on gum, right tarsal and right hallux region. Tarsal and hallux region were unusual skin collagenous fibroma area found in TSC. Five white macules with diameter 4-5mm were also found on the trunk. Electroencephalography resulted epileptiform discharges originating from left temporal posterior and right temporal. Head MRI showed multiple tubers at bilateral cortical-subortical fronto-temporo-parieto-occipital. The patient was diagnosed as tuberous sclerosis and received 3 types of anti epileptic seizure drugs (levetiracetam, carbamazepine and vigabatrin). The treatment resulted decrease of seizure frequency. https://www.panafrican-med-journal.com/content/article/28/92/pdf/92.pdf tuberosclerosisunusual locationfibrous plaque |
| spellingShingle | Prastiya Indra Gunawan Darto Saharso Unusual location of fibrous plaque in Indonesian child with tuberosclerosis complex The Pan African Medical Journal tuberosclerosis unusual location fibrous plaque |
| title | Unusual location of fibrous plaque in Indonesian child with tuberosclerosis complex |
| title_full | Unusual location of fibrous plaque in Indonesian child with tuberosclerosis complex |
| title_fullStr | Unusual location of fibrous plaque in Indonesian child with tuberosclerosis complex |
| title_full_unstemmed | Unusual location of fibrous plaque in Indonesian child with tuberosclerosis complex |
| title_short | Unusual location of fibrous plaque in Indonesian child with tuberosclerosis complex |
| title_sort | unusual location of fibrous plaque in indonesian child with tuberosclerosis complex |
| topic | tuberosclerosis unusual location fibrous plaque |
| url |
https://www.panafrican-med-journal.com/content/article/28/92/pdf/92.pdf
|
| work_keys_str_mv | AT prastiyaindragunawan unusuallocationoffibrousplaqueinindonesianchildwithtuberosclerosiscomplex AT dartosaharso unusuallocationoffibrousplaqueinindonesianchildwithtuberosclerosiscomplex |