The Microbiome-Gut-Brain Axis and Resilience to Developing Anxiety or Depression under Stress
Episodes of depression and anxiety commonly follow the experience of stress, however not everyone who experiences stress develops a mood disorder. Individuals who are able to experience stress without a negative emotional effect are considered stress resilient. Stress-resilience (and its counterpart...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-03-01
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| Series: | Microorganisms |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2607/9/4/723 |
| _version_ | 1797539400665530368 |
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| author | Tracey Bear Julie Dalziel Jane Coad Nicole Roy Christine Butts Pramod Gopal |
| author_facet | Tracey Bear Julie Dalziel Jane Coad Nicole Roy Christine Butts Pramod Gopal |
| author_sort | Tracey Bear |
| collection | DOAJ |
| description | Episodes of depression and anxiety commonly follow the experience of stress, however not everyone who experiences stress develops a mood disorder. Individuals who are able to experience stress without a negative emotional effect are considered stress resilient. Stress-resilience (and its counterpart stress-susceptibility) are influenced by several psychological and biological factors, including the microbiome-gut-brain axis. Emerging research shows that the gut microbiota can influence mood, and that stress is an important variable in this relationship. Stress alters the gut microbiota and plausibly this could contribute to stress-related changes in mood. Most of the reported research has been conducted using animal models and demonstrates a relationship between gut microbiome and mood. The translational evidence from human clinical studies however is rather limited. In this review we examine the microbiome-gut-brain axis research in relation to stress resilience. |
| first_indexed | 2024-03-10T12:44:28Z |
| format | Article |
| id | doaj.art-5e28fb39ed264830a8ae108702d04248 |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-10T12:44:28Z |
| publishDate | 2021-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-5e28fb39ed264830a8ae108702d042482023-11-21T13:34:37ZengMDPI AGMicroorganisms2076-26072021-03-019472310.3390/microorganisms9040723The Microbiome-Gut-Brain Axis and Resilience to Developing Anxiety or Depression under StressTracey Bear0Julie Dalziel1Jane Coad2Nicole Roy3Christine Butts4Pramod Gopal5School of Food and Advanced Technology, Massey University, Palmerston North 4442, New ZealandRiddet Institute, Massey University, Palmerston North 4442, New ZealandSchool of Food and Advanced Technology, Massey University, Palmerston North 4442, New ZealandRiddet Institute, Massey University, Palmerston North 4442, New ZealandThe New Zealand Institute for Plant and Food Research Limited, Palmerston North 4410, New ZealandThe New Zealand Institute for Plant and Food Research Limited, Palmerston North 4410, New ZealandEpisodes of depression and anxiety commonly follow the experience of stress, however not everyone who experiences stress develops a mood disorder. Individuals who are able to experience stress without a negative emotional effect are considered stress resilient. Stress-resilience (and its counterpart stress-susceptibility) are influenced by several psychological and biological factors, including the microbiome-gut-brain axis. Emerging research shows that the gut microbiota can influence mood, and that stress is an important variable in this relationship. Stress alters the gut microbiota and plausibly this could contribute to stress-related changes in mood. Most of the reported research has been conducted using animal models and demonstrates a relationship between gut microbiome and mood. The translational evidence from human clinical studies however is rather limited. In this review we examine the microbiome-gut-brain axis research in relation to stress resilience.https://www.mdpi.com/2076-2607/9/4/723anxietydepressionmoodgut microbiotastressprobiotics |
| spellingShingle | Tracey Bear Julie Dalziel Jane Coad Nicole Roy Christine Butts Pramod Gopal The Microbiome-Gut-Brain Axis and Resilience to Developing Anxiety or Depression under Stress Microorganisms anxiety depression mood gut microbiota stress probiotics |
| title | The Microbiome-Gut-Brain Axis and Resilience to Developing Anxiety or Depression under Stress |
| title_full | The Microbiome-Gut-Brain Axis and Resilience to Developing Anxiety or Depression under Stress |
| title_fullStr | The Microbiome-Gut-Brain Axis and Resilience to Developing Anxiety or Depression under Stress |
| title_full_unstemmed | The Microbiome-Gut-Brain Axis and Resilience to Developing Anxiety or Depression under Stress |
| title_short | The Microbiome-Gut-Brain Axis and Resilience to Developing Anxiety or Depression under Stress |
| title_sort | microbiome gut brain axis and resilience to developing anxiety or depression under stress |
| topic | anxiety depression mood gut microbiota stress probiotics |
| url | https://www.mdpi.com/2076-2607/9/4/723 |
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