The Osteosarcoma Microenvironment: A Complex but Targetable Ecosystem

The Osteosarcoma Microenvironment: A Complex but Targetable Ecosystem

Osteosarcomas are the most frequent primary bone sarcomas, affecting mainly children, adolescents, and young adults, and with a second peak of incidence in elderly individuals. The current therapeutic management, a combined regimen of poly-chemotherapy and surgery, still remains largely insufficient...

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Bibliographic Details
Main Authors: Isabelle Corre, Franck Verrecchia, Vincent Crenn, Francoise Redini, Valérie Trichet
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
Osteosarcoma
microenvironment
bone
stromal cells
vascular cells
targeted therapies
Online Access:https://www.mdpi.com/2073-4409/9/4/976

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