Ubiquitin–proteasome system and the role of its inhibitors in cancer therapy
Despite all the other cells that have the potential to prevent cancer development and metastasis through tumour suppressor proteins, cancer cells can upregulate the ubiquitin–proteasome system (UPS) by which they can degrade tumour suppressor proteins and avoid apoptosis. This system plays an extens...
Main Authors: | Fatemeh Aliabadi, Beheshteh Sohrabi, Ebrahim Mostafavi, Hamidreza Pazoki-Toroudi, Thomas J. Webster |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2021-04-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/10.1098/rsob.200390 |
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