Effects of non-pharmacological or pharmacological interventions to promote cognition and brain plasticity in aging individuals

Brain aging and aging-related neurodegenerative disorders are major health challenges faced by modern societies. Brain aging is associated with cognitive and functional decline and represents the favourable background for the onset and development of dementia. Brain aging is associated with early...

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Main Authors: Valentina ePieramico, Roberto eEsposito, Stefano eCesinaro, Valerio eFrazzini, Stefano Luca Sensi
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Systems Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsys.2014.00153/full
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author Valentina ePieramico
Roberto eEsposito
Stefano eCesinaro
Valerio eFrazzini
Stefano Luca Sensi
Stefano Luca Sensi
Stefano Luca Sensi
author_facet Valentina ePieramico
Roberto eEsposito
Stefano eCesinaro
Valerio eFrazzini
Stefano Luca Sensi
Stefano Luca Sensi
Stefano Luca Sensi
author_sort Valentina ePieramico
collection DOAJ
description Brain aging and aging-related neurodegenerative disorders are major health challenges faced by modern societies. Brain aging is associated with cognitive and functional decline and represents the favourable background for the onset and development of dementia. Brain aging is associated with early and subtle anatomo-functional physiological changes that often precede the appearance of clinical signs of cognitive decline. Neuroimaging approaches unveiled the functional correlates of these alterations and helped in the identification of therapeutic targets that can be potentially useful in counteracting age-dependent cognitive decline.A growing body of evidence supports the notion that cognitive stimulation and aerobic training can preserve and enhance operational skills in elderly individuals as well as reduce the incidence of dementia. This review aims at providing an extensive and critical overview of the most recent data that support the efficacy of non-pharmacological and pharmacological interventions aimed at enhancing cognition and brain plasticity in healthy elderly individuals as well as delaying the cognitive decline associated with dementia.
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spelling doaj.art-5e2ab16479b94108afd553d526300c9f2022-12-22T02:41:59ZengFrontiers Media S.A.Frontiers in Systems Neuroscience1662-51372014-09-01810.3389/fnsys.2014.00153107321Effects of non-pharmacological or pharmacological interventions to promote cognition and brain plasticity in aging individualsValentina ePieramico0Roberto eEsposito1Stefano eCesinaro2Valerio eFrazzini3Stefano Luca Sensi4Stefano Luca Sensi5Stefano Luca Sensi6Molecular Neurology UnitUniversity “G. d’Annunzio”, Chieti-PescaraMolecular Neurology UnitMolecular Neurology UnitUniversity of California, IrvineMolecular Neurology UnitUniversity “G. d’Annunzio”, Chieti-PescaraBrain aging and aging-related neurodegenerative disorders are major health challenges faced by modern societies. Brain aging is associated with cognitive and functional decline and represents the favourable background for the onset and development of dementia. Brain aging is associated with early and subtle anatomo-functional physiological changes that often precede the appearance of clinical signs of cognitive decline. Neuroimaging approaches unveiled the functional correlates of these alterations and helped in the identification of therapeutic targets that can be potentially useful in counteracting age-dependent cognitive decline.A growing body of evidence supports the notion that cognitive stimulation and aerobic training can preserve and enhance operational skills in elderly individuals as well as reduce the incidence of dementia. This review aims at providing an extensive and critical overview of the most recent data that support the efficacy of non-pharmacological and pharmacological interventions aimed at enhancing cognition and brain plasticity in healthy elderly individuals as well as delaying the cognitive decline associated with dementia.http://journal.frontiersin.org/Journal/10.3389/fnsys.2014.00153/fullNeuronal PlasticityBrain agingnon-pharmacological interventionscognitive enhancing drugscognitive enrichment
spellingShingle Valentina ePieramico
Roberto eEsposito
Stefano eCesinaro
Valerio eFrazzini
Stefano Luca Sensi
Stefano Luca Sensi
Stefano Luca Sensi
Effects of non-pharmacological or pharmacological interventions to promote cognition and brain plasticity in aging individuals
Frontiers in Systems Neuroscience
Neuronal Plasticity
Brain aging
non-pharmacological interventions
cognitive enhancing drugs
cognitive enrichment
title Effects of non-pharmacological or pharmacological interventions to promote cognition and brain plasticity in aging individuals
title_full Effects of non-pharmacological or pharmacological interventions to promote cognition and brain plasticity in aging individuals
title_fullStr Effects of non-pharmacological or pharmacological interventions to promote cognition and brain plasticity in aging individuals
title_full_unstemmed Effects of non-pharmacological or pharmacological interventions to promote cognition and brain plasticity in aging individuals
title_short Effects of non-pharmacological or pharmacological interventions to promote cognition and brain plasticity in aging individuals
title_sort effects of non pharmacological or pharmacological interventions to promote cognition and brain plasticity in aging individuals
topic Neuronal Plasticity
Brain aging
non-pharmacological interventions
cognitive enhancing drugs
cognitive enrichment
url http://journal.frontiersin.org/Journal/10.3389/fnsys.2014.00153/full
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