Effects of non-pharmacological or pharmacological interventions to promote cognition and brain plasticity in aging individuals
Brain aging and aging-related neurodegenerative disorders are major health challenges faced by modern societies. Brain aging is associated with cognitive and functional decline and represents the favourable background for the onset and development of dementia. Brain aging is associated with early...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2014-09-01
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Series: | Frontiers in Systems Neuroscience |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnsys.2014.00153/full |
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author | Valentina ePieramico Roberto eEsposito Stefano eCesinaro Valerio eFrazzini Stefano Luca Sensi Stefano Luca Sensi Stefano Luca Sensi |
author_facet | Valentina ePieramico Roberto eEsposito Stefano eCesinaro Valerio eFrazzini Stefano Luca Sensi Stefano Luca Sensi Stefano Luca Sensi |
author_sort | Valentina ePieramico |
collection | DOAJ |
description | Brain aging and aging-related neurodegenerative disorders are major health challenges faced by modern societies. Brain aging is associated with cognitive and functional decline and represents the favourable background for the onset and development of dementia. Brain aging is associated with early and subtle anatomo-functional physiological changes that often precede the appearance of clinical signs of cognitive decline. Neuroimaging approaches unveiled the functional correlates of these alterations and helped in the identification of therapeutic targets that can be potentially useful in counteracting age-dependent cognitive decline.A growing body of evidence supports the notion that cognitive stimulation and aerobic training can preserve and enhance operational skills in elderly individuals as well as reduce the incidence of dementia. This review aims at providing an extensive and critical overview of the most recent data that support the efficacy of non-pharmacological and pharmacological interventions aimed at enhancing cognition and brain plasticity in healthy elderly individuals as well as delaying the cognitive decline associated with dementia. |
first_indexed | 2024-04-13T15:12:17Z |
format | Article |
id | doaj.art-5e2ab16479b94108afd553d526300c9f |
institution | Directory Open Access Journal |
issn | 1662-5137 |
language | English |
last_indexed | 2024-04-13T15:12:17Z |
publishDate | 2014-09-01 |
publisher | Frontiers Media S.A. |
record_format | Article |
series | Frontiers in Systems Neuroscience |
spelling | doaj.art-5e2ab16479b94108afd553d526300c9f2022-12-22T02:41:59ZengFrontiers Media S.A.Frontiers in Systems Neuroscience1662-51372014-09-01810.3389/fnsys.2014.00153107321Effects of non-pharmacological or pharmacological interventions to promote cognition and brain plasticity in aging individualsValentina ePieramico0Roberto eEsposito1Stefano eCesinaro2Valerio eFrazzini3Stefano Luca Sensi4Stefano Luca Sensi5Stefano Luca Sensi6Molecular Neurology UnitUniversity “G. d’Annunzio”, Chieti-PescaraMolecular Neurology UnitMolecular Neurology UnitUniversity of California, IrvineMolecular Neurology UnitUniversity “G. d’Annunzio”, Chieti-PescaraBrain aging and aging-related neurodegenerative disorders are major health challenges faced by modern societies. Brain aging is associated with cognitive and functional decline and represents the favourable background for the onset and development of dementia. Brain aging is associated with early and subtle anatomo-functional physiological changes that often precede the appearance of clinical signs of cognitive decline. Neuroimaging approaches unveiled the functional correlates of these alterations and helped in the identification of therapeutic targets that can be potentially useful in counteracting age-dependent cognitive decline.A growing body of evidence supports the notion that cognitive stimulation and aerobic training can preserve and enhance operational skills in elderly individuals as well as reduce the incidence of dementia. This review aims at providing an extensive and critical overview of the most recent data that support the efficacy of non-pharmacological and pharmacological interventions aimed at enhancing cognition and brain plasticity in healthy elderly individuals as well as delaying the cognitive decline associated with dementia.http://journal.frontiersin.org/Journal/10.3389/fnsys.2014.00153/fullNeuronal PlasticityBrain agingnon-pharmacological interventionscognitive enhancing drugscognitive enrichment |
spellingShingle | Valentina ePieramico Roberto eEsposito Stefano eCesinaro Valerio eFrazzini Stefano Luca Sensi Stefano Luca Sensi Stefano Luca Sensi Effects of non-pharmacological or pharmacological interventions to promote cognition and brain plasticity in aging individuals Frontiers in Systems Neuroscience Neuronal Plasticity Brain aging non-pharmacological interventions cognitive enhancing drugs cognitive enrichment |
title | Effects of non-pharmacological or pharmacological interventions to promote cognition and brain plasticity in aging individuals |
title_full | Effects of non-pharmacological or pharmacological interventions to promote cognition and brain plasticity in aging individuals |
title_fullStr | Effects of non-pharmacological or pharmacological interventions to promote cognition and brain plasticity in aging individuals |
title_full_unstemmed | Effects of non-pharmacological or pharmacological interventions to promote cognition and brain plasticity in aging individuals |
title_short | Effects of non-pharmacological or pharmacological interventions to promote cognition and brain plasticity in aging individuals |
title_sort | effects of non pharmacological or pharmacological interventions to promote cognition and brain plasticity in aging individuals |
topic | Neuronal Plasticity Brain aging non-pharmacological interventions cognitive enhancing drugs cognitive enrichment |
url | http://journal.frontiersin.org/Journal/10.3389/fnsys.2014.00153/full |
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