In-hospital mortality among a cohort of cirrhotic patients admitted to a Tertiary Hospital

Background/Aim : To determine the mortality rate in a cohort of hospitalized patients with cirrhosis and examine their resuscitation status at admission. Materials and Methods : A retrospective chart review was conducted of patients with cirrhosis who were admitted to a tertiary care hospital in Riy...

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Main Authors: Mohammad A Alsultan, Rashed S Alrshed, Abdulrahman A Aljumah, Salim A Baharoon, Yaseen M Arabi, Abdulaziz S Aldawood
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-01-01
Series:The Saudi Journal of Gastroenterology
Subjects:
Online Access:http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2011;volume=17;issue=6;spage=387;epage=390;aulast=Alsultan
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author Mohammad A Alsultan
Rashed S Alrshed
Abdulrahman A Aljumah
Salim A Baharoon
Yaseen M Arabi
Abdulaziz S Aldawood
author_facet Mohammad A Alsultan
Rashed S Alrshed
Abdulrahman A Aljumah
Salim A Baharoon
Yaseen M Arabi
Abdulaziz S Aldawood
author_sort Mohammad A Alsultan
collection DOAJ
description Background/Aim : To determine the mortality rate in a cohort of hospitalized patients with cirrhosis and examine their resuscitation status at admission. Materials and Methods : A retrospective chart review was conducted of patients with cirrhosis who were admitted to a tertiary care hospital in Riyadh, Saudi Arabia, from January 1, 2009, to December 31, 2009. Results: We reviewed 226 cirrhotic patients during the study period. The hospital mortality rate was 35%. A univariate analysis revealed that worse outcomes were seen in patients with advanced age or who had worse child-turcotte-pugh (CPT) scores, worse model for end-stage liver disease (MELD) scores, low albumin and high serum creatinine. Using a multivariate analysis, we found that advanced age (P=0.004) and high MELD (P=0.001) scores were independent risk factors for the mortality of cirrhotic patients. The end-of-life decision were made in 34% of cirrhotic patients, and the majority of deceased patients were "no resuscitation" status (90% vs. 4%, P<0.001). Conclusions : The relatively high mortality in cirrhotic patients admitted for care in a tertiary hospital, Saudi Arabia was comparable to that reported in the literature. Furthermore, end-of-life discussions should be addressed early in the hospitalization of cirrhotic patients.
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spelling doaj.art-5e2ddebfa94b4e14a394f2dc0a8fe9392022-12-22T03:57:40ZengWolters Kluwer Medknow PublicationsThe Saudi Journal of Gastroenterology1319-37671998-40492011-01-0117638739010.4103/1319-3767.87179In-hospital mortality among a cohort of cirrhotic patients admitted to a Tertiary HospitalMohammad A AlsultanRashed S AlrshedAbdulrahman A AljumahSalim A BaharoonYaseen M ArabiAbdulaziz S AldawoodBackground/Aim : To determine the mortality rate in a cohort of hospitalized patients with cirrhosis and examine their resuscitation status at admission. Materials and Methods : A retrospective chart review was conducted of patients with cirrhosis who were admitted to a tertiary care hospital in Riyadh, Saudi Arabia, from January 1, 2009, to December 31, 2009. Results: We reviewed 226 cirrhotic patients during the study period. The hospital mortality rate was 35%. A univariate analysis revealed that worse outcomes were seen in patients with advanced age or who had worse child-turcotte-pugh (CPT) scores, worse model for end-stage liver disease (MELD) scores, low albumin and high serum creatinine. Using a multivariate analysis, we found that advanced age (P=0.004) and high MELD (P=0.001) scores were independent risk factors for the mortality of cirrhotic patients. The end-of-life decision were made in 34% of cirrhotic patients, and the majority of deceased patients were "no resuscitation" status (90% vs. 4%, P<0.001). Conclusions : The relatively high mortality in cirrhotic patients admitted for care in a tertiary hospital, Saudi Arabia was comparable to that reported in the literature. Furthermore, end-of-life discussions should be addressed early in the hospitalization of cirrhotic patients.http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2011;volume=17;issue=6;spage=387;epage=390;aulast=AlsultanCirrhosisMELD scoremortality
spellingShingle Mohammad A Alsultan
Rashed S Alrshed
Abdulrahman A Aljumah
Salim A Baharoon
Yaseen M Arabi
Abdulaziz S Aldawood
In-hospital mortality among a cohort of cirrhotic patients admitted to a Tertiary Hospital
The Saudi Journal of Gastroenterology
Cirrhosis
MELD score
mortality
title In-hospital mortality among a cohort of cirrhotic patients admitted to a Tertiary Hospital
title_full In-hospital mortality among a cohort of cirrhotic patients admitted to a Tertiary Hospital
title_fullStr In-hospital mortality among a cohort of cirrhotic patients admitted to a Tertiary Hospital
title_full_unstemmed In-hospital mortality among a cohort of cirrhotic patients admitted to a Tertiary Hospital
title_short In-hospital mortality among a cohort of cirrhotic patients admitted to a Tertiary Hospital
title_sort in hospital mortality among a cohort of cirrhotic patients admitted to a tertiary hospital
topic Cirrhosis
MELD score
mortality
url http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2011;volume=17;issue=6;spage=387;epage=390;aulast=Alsultan
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