Family dementia caregivers with suicidal ideation improve with mentalizing imagery therapy: Results from a pilot study

Background: Family caregivers of persons living with dementia often experience increased depression and suicidal ideation (SI). However, the feasibility and impact of therapies on caregiver SI has remained largely unexplored. Mentalizing imagery therapy (MIT) helps reduce psychological symptoms thro...

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Main Authors: Saira Madarasmi, Paulina Gutierrez-Ramirez, Nader Barsoum, Sreya Banerjee, Liliana Ramirez Gomez, Maria Melero-Dominguez, Laura N. Gitlin, Aderonke Pederson, Richard T. Liu, Felipe A. Jain
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Journal of Affective Disorders Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666915324000064
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author Saira Madarasmi
Paulina Gutierrez-Ramirez
Nader Barsoum
Sreya Banerjee
Liliana Ramirez Gomez
Maria Melero-Dominguez
Laura N. Gitlin
Aderonke Pederson
Richard T. Liu
Felipe A. Jain
author_facet Saira Madarasmi
Paulina Gutierrez-Ramirez
Nader Barsoum
Sreya Banerjee
Liliana Ramirez Gomez
Maria Melero-Dominguez
Laura N. Gitlin
Aderonke Pederson
Richard T. Liu
Felipe A. Jain
author_sort Saira Madarasmi
collection DOAJ
description Background: Family caregivers of persons living with dementia often experience increased depression and suicidal ideation (SI). However, the feasibility and impact of therapies on caregiver SI has remained largely unexplored. Mentalizing imagery therapy (MIT) helps reduce psychological symptoms through mindfulness and guided imagery. This pilot study examined the feasibility of participation by caregivers with SI in a randomized controlled trial (RCT) of MIT versus a psychosocial support group (SG), and the respective impact of group on SI, depression, and secondary outcomes. Methods: A secondary analysis of data from an RCT of 4-week MIT or SG for caregivers (n = 46) was performed, identifying SI (n = 23) and non-SI (n = 23) cohorts. Group attendance and home practice were compared between cohorts. In the SI cohort (total n = 23, MIT n = 11, SG n = 12), group differences in SI, depression, and secondary outcomes were evaluated post-group and at 4-month follow-up. Results: Attendance in both groups and home practice in MIT were similar between SI and non-SI cohorts. In the SI cohort, MIT evinced greater improvements relative to SG in SI (p=.02) and depression (p=.02) post-group, and other secondary outcomes at follow-up. Limitations: Limitations include small sample size and single-item assessments of SI from validated depression rating scales. Conclusions: Participation in an RCT was feasible for caregivers with SI. MIT resulted in important benefits for SI and depression, while SG showed no acute SI benefit. The role of MIT in improving SI should be confirmed with adequately powered trials, as effective therapies to address caregiver SI are critical.
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spelling doaj.art-5e2df0a1e89d4470968d076a459e44f72024-01-19T05:03:29ZengElsevierJournal of Affective Disorders Reports2666-91532024-04-0116100721Family dementia caregivers with suicidal ideation improve with mentalizing imagery therapy: Results from a pilot studySaira Madarasmi0Paulina Gutierrez-Ramirez1Nader Barsoum2Sreya Banerjee3Liliana Ramirez Gomez4Maria Melero-Dominguez5Laura N. Gitlin6Aderonke Pederson7Richard T. Liu8Felipe A. Jain9Department of Psychiatry, Depression Clinical and Research Program, Massachusetts General Hospital, Boston, MA, United StatesDepartment of Psychiatry, Depression Clinical and Research Program, Massachusetts General Hospital, Boston, MA, United StatesDepartment of Psychiatry, Depression Clinical and Research Program, Massachusetts General Hospital, Boston, MA, United StatesDepartment of Psychiatry, Depression Clinical and Research Program, Massachusetts General Hospital, Boston, MA, United States; Harvard Medical School, Boston, MA, United StatesHarvard Medical School, Boston, MA, United States; Department of Neurology, Massachusetts General Hospital, Boston, MA, United StatesDepartment of Psychiatry, Depression Clinical and Research Program, Massachusetts General Hospital, Boston, MA, United StatesCollege of Nursing and Health Professions, Drexel University, Philadelphia, PA, United StatesDepartment of Psychiatry, Depression Clinical and Research Program, Massachusetts General Hospital, Boston, MA, United States; Harvard Medical School, Boston, MA, United StatesDepartment of Psychiatry, Depression Clinical and Research Program, Massachusetts General Hospital, Boston, MA, United States; Harvard Medical School, Boston, MA, United StatesDepartment of Psychiatry, Depression Clinical and Research Program, Massachusetts General Hospital, Boston, MA, United States; Harvard Medical School, Boston, MA, United States; Harvard-Massachusetts Institute of Technology (MIT) Division of Health Sciences and Technology, Boston, MA, United States; Corresponding author at: Department of Psychiatry, Depression Clinical and Research Program, One Bowdoin Square, 6th Floor, Boston, MA 02114, United States.Background: Family caregivers of persons living with dementia often experience increased depression and suicidal ideation (SI). However, the feasibility and impact of therapies on caregiver SI has remained largely unexplored. Mentalizing imagery therapy (MIT) helps reduce psychological symptoms through mindfulness and guided imagery. This pilot study examined the feasibility of participation by caregivers with SI in a randomized controlled trial (RCT) of MIT versus a psychosocial support group (SG), and the respective impact of group on SI, depression, and secondary outcomes. Methods: A secondary analysis of data from an RCT of 4-week MIT or SG for caregivers (n = 46) was performed, identifying SI (n = 23) and non-SI (n = 23) cohorts. Group attendance and home practice were compared between cohorts. In the SI cohort (total n = 23, MIT n = 11, SG n = 12), group differences in SI, depression, and secondary outcomes were evaluated post-group and at 4-month follow-up. Results: Attendance in both groups and home practice in MIT were similar between SI and non-SI cohorts. In the SI cohort, MIT evinced greater improvements relative to SG in SI (p=.02) and depression (p=.02) post-group, and other secondary outcomes at follow-up. Limitations: Limitations include small sample size and single-item assessments of SI from validated depression rating scales. Conclusions: Participation in an RCT was feasible for caregivers with SI. MIT resulted in important benefits for SI and depression, while SG showed no acute SI benefit. The role of MIT in improving SI should be confirmed with adequately powered trials, as effective therapies to address caregiver SI are critical.http://www.sciencedirect.com/science/article/pii/S2666915324000064Family caregiversDementiaMindfulnessDepressionSuicidal ideationGuided imagery
spellingShingle Saira Madarasmi
Paulina Gutierrez-Ramirez
Nader Barsoum
Sreya Banerjee
Liliana Ramirez Gomez
Maria Melero-Dominguez
Laura N. Gitlin
Aderonke Pederson
Richard T. Liu
Felipe A. Jain
Family dementia caregivers with suicidal ideation improve with mentalizing imagery therapy: Results from a pilot study
Journal of Affective Disorders Reports
Family caregivers
Dementia
Mindfulness
Depression
Suicidal ideation
Guided imagery
title Family dementia caregivers with suicidal ideation improve with mentalizing imagery therapy: Results from a pilot study
title_full Family dementia caregivers with suicidal ideation improve with mentalizing imagery therapy: Results from a pilot study
title_fullStr Family dementia caregivers with suicidal ideation improve with mentalizing imagery therapy: Results from a pilot study
title_full_unstemmed Family dementia caregivers with suicidal ideation improve with mentalizing imagery therapy: Results from a pilot study
title_short Family dementia caregivers with suicidal ideation improve with mentalizing imagery therapy: Results from a pilot study
title_sort family dementia caregivers with suicidal ideation improve with mentalizing imagery therapy results from a pilot study
topic Family caregivers
Dementia
Mindfulness
Depression
Suicidal ideation
Guided imagery
url http://www.sciencedirect.com/science/article/pii/S2666915324000064
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