Printed Capillary Microfluidic Devices and Their Application in Biosensing

Microfluidic devices with a free-standing structure were printed directly on polymer films using the functional materials that form interconnected pores. The printed devices can transport fluids by capillary action in the same fashion as paper-based microfluidic devices, and they can handle much sma...

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Main Authors: Zhiyi Zhang, Stephen Lang, Kate Pearson, Yawar Farhan, Ye Tao, Gaozhi Xiao
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Micromachines
Subjects:
Online Access:https://www.mdpi.com/2072-666X/14/11/2059
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author Zhiyi Zhang
Stephen Lang
Kate Pearson
Yawar Farhan
Ye Tao
Gaozhi Xiao
author_facet Zhiyi Zhang
Stephen Lang
Kate Pearson
Yawar Farhan
Ye Tao
Gaozhi Xiao
author_sort Zhiyi Zhang
collection DOAJ
description Microfluidic devices with a free-standing structure were printed directly on polymer films using the functional materials that form interconnected pores. The printed devices can transport fluids by capillary action in the same fashion as paper-based microfluidic devices, and they can handle much smaller sample volumes than typical paper-based devices. Detection of glucose was performed using both colorimetric and electrochemical methods, and the observed limits of detection (LOD) were similar to those obtained with paper-based microfluidic devices under comparable testing conditions. It is demonstrated that printed microfluidic devices can be fabricated using printing processes that are suitable for high-volume and low-cost production and that the integration of microfluidic channels with electrodes is straightforward with printing. Several materials that are printable and form interconnected pores are presented.
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spelling doaj.art-5e2eae5c37a9484f83cc5a43a77be9d12023-11-24T14:56:25ZengMDPI AGMicromachines2072-666X2023-11-011411205910.3390/mi14112059Printed Capillary Microfluidic Devices and Their Application in BiosensingZhiyi Zhang0Stephen Lang1Kate Pearson2Yawar Farhan3Ye Tao4Gaozhi Xiao5Advanced Electronic and Photonic Research Center, National Research Council Canada, Ottawa, ON K1A 0R6, CanadaAdvanced Electronic and Photonic Research Center, National Research Council Canada, Ottawa, ON K1A 0R6, CanadaAdvanced Electronic and Photonic Research Center, National Research Council Canada, Ottawa, ON K1A 0R6, CanadaAdvanced Electronic and Photonic Research Center, National Research Council Canada, Ottawa, ON K1A 0R6, CanadaAdvanced Electronic and Photonic Research Center, National Research Council Canada, Ottawa, ON K1A 0R6, CanadaAdvanced Electronic and Photonic Research Center, National Research Council Canada, Ottawa, ON K1A 0R6, CanadaMicrofluidic devices with a free-standing structure were printed directly on polymer films using the functional materials that form interconnected pores. The printed devices can transport fluids by capillary action in the same fashion as paper-based microfluidic devices, and they can handle much smaller sample volumes than typical paper-based devices. Detection of glucose was performed using both colorimetric and electrochemical methods, and the observed limits of detection (LOD) were similar to those obtained with paper-based microfluidic devices under comparable testing conditions. It is demonstrated that printed microfluidic devices can be fabricated using printing processes that are suitable for high-volume and low-cost production and that the integration of microfluidic channels with electrodes is straightforward with printing. Several materials that are printable and form interconnected pores are presented.https://www.mdpi.com/2072-666X/14/11/2059microfluidic devicesporous materialsprintingcapillary-driven flowbiosensing
spellingShingle Zhiyi Zhang
Stephen Lang
Kate Pearson
Yawar Farhan
Ye Tao
Gaozhi Xiao
Printed Capillary Microfluidic Devices and Their Application in Biosensing
Micromachines
microfluidic devices
porous materials
printing
capillary-driven flow
biosensing
title Printed Capillary Microfluidic Devices and Their Application in Biosensing
title_full Printed Capillary Microfluidic Devices and Their Application in Biosensing
title_fullStr Printed Capillary Microfluidic Devices and Their Application in Biosensing
title_full_unstemmed Printed Capillary Microfluidic Devices and Their Application in Biosensing
title_short Printed Capillary Microfluidic Devices and Their Application in Biosensing
title_sort printed capillary microfluidic devices and their application in biosensing
topic microfluidic devices
porous materials
printing
capillary-driven flow
biosensing
url https://www.mdpi.com/2072-666X/14/11/2059
work_keys_str_mv AT zhiyizhang printedcapillarymicrofluidicdevicesandtheirapplicationinbiosensing
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AT katepearson printedcapillarymicrofluidicdevicesandtheirapplicationinbiosensing
AT yawarfarhan printedcapillarymicrofluidicdevicesandtheirapplicationinbiosensing
AT yetao printedcapillarymicrofluidicdevicesandtheirapplicationinbiosensing
AT gaozhixiao printedcapillarymicrofluidicdevicesandtheirapplicationinbiosensing