miR-30a-5p promotes glomerular podocyte <?A3B2 tlsb=-0.06w?>apoptosis via DNMT1-mediated hypermethylation under hyperhomocysteinemia<?A3B2 tlsb?>

miR-30a-5p promotes glomerular podocyte <?A3B2 tlsb=-0.06w?>apoptosis via DNMT1-mediated hypermethylation under hyperhomocysteinemia<?A3B2 tlsb?>

Abnormal elevation of homocysteine (Hcy) level is closely related to the development and progression of chronic kidney disease (CKD), with the molecular mech2anisms that are not fully elucidated. Given the demonstration that miR-30a-5p is specifically expressed in glomerular podocytes, in the presen...

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Bibliographic Details
Main Authors: Ding Ning, Xie Lin, Ma Fei, Ma Shengchao, Xiong Jiantuan, Lu Guanjun, Zhang Huiping, Jiang Yideng
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2021-12-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
miR-30a-5p
DNA methylation
podocyte apoptosis
FOXA1
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2021005

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