Comprehensive SNP array study of frequently used neuroblastoma cell lines; copy neutral loss of heterozygosity is common in the cell lines but uncommon in primary tumors

Comprehensive SNP array study of frequently used neuroblastoma cell lines; copy neutral loss of heterozygosity is common in the cell lines but uncommon in primary tumors

<p>Abstract</p> <p>Background</p> <p>Copy neutral loss of heterozygosity (CN-LOH) refers to a special case of LOH occurring without any resulting loss in copy number. These alterations is sometimes seen in tumors as a way to inactivate a tumor suppressor gene and have b...

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Bibliographic Details
Main Authors:	Kogner Per, Abrahamsson Jonas, Sjöberg Rose-Marie, Erichsen Jennie, Carén Helena, Kryh Hanna, Martinsson Tommy
Format:	Article
Language:	English
Published:	BMC 2011-09-01
Series:	BMC Genomics
Online Access:	http://www.biomedcentral.com/1471-2164/12/443

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