Attributes influencing parental decision-making to receive the Tdap vaccine to reduce the risk of pertussis transmission to their newborn – outcome of a cross-sectional conjoint experiment in Spain and Italy
Pertussis vaccination of parents and household contacts (‘cocooning’) to protect newborn infants is an established strategy in many countries, although uptake may be low. Many aspects may influence such decision-making. We conducted a cross-sectional survey (NCT01890447) of households and other clos...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2019-05-01
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| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/21645515.2019.1571890 |
| _version_ | 1827809714230001664 |
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| author | Edouard Ledent Giovanni Gabutti Esther W. de Bekker-Grob Juan Luis Alcázar Zambrano Magda Campins Martí María Teresa Del Hierro Gurruchaga María José Fernández Cruz Giuseppe Ferrera Francesca Fortunato Pierfederico Torchio Giorgio Zoppi Christian Agboton Walid Kandeil Federico Marchetti |
| author_facet | Edouard Ledent Giovanni Gabutti Esther W. de Bekker-Grob Juan Luis Alcázar Zambrano Magda Campins Martí María Teresa Del Hierro Gurruchaga María José Fernández Cruz Giuseppe Ferrera Francesca Fortunato Pierfederico Torchio Giorgio Zoppi Christian Agboton Walid Kandeil Federico Marchetti |
| author_sort | Edouard Ledent |
| collection | DOAJ |
| description | Pertussis vaccination of parents and household contacts (‘cocooning’) to protect newborn infants is an established strategy in many countries, although uptake may be low. Many aspects may influence such decision-making. We conducted a cross-sectional survey (NCT01890447) of households and other close contacts of newborns aged ≤6 months (or of expectant mothers in their last trimester) in Spain and Italy, using an adaptive discrete-choice experiment questionnaire. Aims were to assess the relative importance of attributes influencing vaccine adoption, and to estimate variation in vaccine adoption rates and the impact of cost on vaccination rates. Six hundred and fifteen participants (Spain, n = 313; Italy, n = 302) completed the survey. Of 144 available questionnaire scenarios, the most frequently selected (14% of respondents in both countries) were infant protection by household vaccination at vaccination center, recommendation by family physician and health authorities, with information available on leaflets and websites. The attribute with highest median relative importance was ‘reduction in source of infection’ in Spain (23.1%) and ‘vaccination location’ in Italy (18.8%). Differences between other attributes were low in both countries, with media attributes showing low importance. Over 80% of respondents indicated a definite or probable response to vaccine adoption (at no-cost) with estimated probability of adoption of 89–98%; applying vaccine costs (25€ per person) would reduce the probability of uptake by 7–20% in definite/probable respondents. Awareness of these determinants is helpful in informing Health Authorities and healthcare practitioners implementing a cocooning strategy for those populations where maternal immunization is not a preferred option. |
| first_indexed | 2024-03-11T22:44:47Z |
| format | Article |
| id | doaj.art-5e3837e88aea484e8cad8d11d7bb9b6b |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T22:44:47Z |
| publishDate | 2019-05-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-5e3837e88aea484e8cad8d11d7bb9b6b2023-09-22T08:38:25ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2019-05-011551080109110.1080/21645515.2019.15718901571890Attributes influencing parental decision-making to receive the Tdap vaccine to reduce the risk of pertussis transmission to their newborn – outcome of a cross-sectional conjoint experiment in Spain and ItalyEdouard Ledent0Giovanni Gabutti1Esther W. de Bekker-Grob2Juan Luis Alcázar Zambrano3Magda Campins Martí4María Teresa Del Hierro Gurruchaga5María José Fernández Cruz6Giuseppe Ferrera7Francesca Fortunato8Pierfederico Torchio9Giorgio Zoppi10Christian Agboton11Walid Kandeil12Federico Marchetti13GSKUniversity of FerraraErasmus School of Health Policy & Management, Erasmus University RotterdamClínica Universitad de NavarraHospital Universitario Vall d’HebronUniversidad del País VascoHospital Universitario de GetafeASP Ragusa, Centro ServiziUniversity of FoggiaServizio Igiene e Sanità PubblicaStruttura Complessa Igiene e Sanità PubblicaGSKGSKGSKPertussis vaccination of parents and household contacts (‘cocooning’) to protect newborn infants is an established strategy in many countries, although uptake may be low. Many aspects may influence such decision-making. We conducted a cross-sectional survey (NCT01890447) of households and other close contacts of newborns aged ≤6 months (or of expectant mothers in their last trimester) in Spain and Italy, using an adaptive discrete-choice experiment questionnaire. Aims were to assess the relative importance of attributes influencing vaccine adoption, and to estimate variation in vaccine adoption rates and the impact of cost on vaccination rates. Six hundred and fifteen participants (Spain, n = 313; Italy, n = 302) completed the survey. Of 144 available questionnaire scenarios, the most frequently selected (14% of respondents in both countries) were infant protection by household vaccination at vaccination center, recommendation by family physician and health authorities, with information available on leaflets and websites. The attribute with highest median relative importance was ‘reduction in source of infection’ in Spain (23.1%) and ‘vaccination location’ in Italy (18.8%). Differences between other attributes were low in both countries, with media attributes showing low importance. Over 80% of respondents indicated a definite or probable response to vaccine adoption (at no-cost) with estimated probability of adoption of 89–98%; applying vaccine costs (25€ per person) would reduce the probability of uptake by 7–20% in definite/probable respondents. Awareness of these determinants is helpful in informing Health Authorities and healthcare practitioners implementing a cocooning strategy for those populations where maternal immunization is not a preferred option.http://dx.doi.org/10.1080/21645515.2019.1571890pertussisvaccinationcocooningspainitalyadaptive choice-based conjoint questionnaireadaptive discrete-choice experimentpreferencessawtooth softwaresurvey |
| spellingShingle | Edouard Ledent Giovanni Gabutti Esther W. de Bekker-Grob Juan Luis Alcázar Zambrano Magda Campins Martí María Teresa Del Hierro Gurruchaga María José Fernández Cruz Giuseppe Ferrera Francesca Fortunato Pierfederico Torchio Giorgio Zoppi Christian Agboton Walid Kandeil Federico Marchetti Attributes influencing parental decision-making to receive the Tdap vaccine to reduce the risk of pertussis transmission to their newborn – outcome of a cross-sectional conjoint experiment in Spain and Italy Human Vaccines & Immunotherapeutics pertussis vaccination cocooning spain italy adaptive choice-based conjoint questionnaire adaptive discrete-choice experiment preferences sawtooth software survey |
| title | Attributes influencing parental decision-making to receive the Tdap vaccine to reduce the risk of pertussis transmission to their newborn – outcome of a cross-sectional conjoint experiment in Spain and Italy |
| title_full | Attributes influencing parental decision-making to receive the Tdap vaccine to reduce the risk of pertussis transmission to their newborn – outcome of a cross-sectional conjoint experiment in Spain and Italy |
| title_fullStr | Attributes influencing parental decision-making to receive the Tdap vaccine to reduce the risk of pertussis transmission to their newborn – outcome of a cross-sectional conjoint experiment in Spain and Italy |
| title_full_unstemmed | Attributes influencing parental decision-making to receive the Tdap vaccine to reduce the risk of pertussis transmission to their newborn – outcome of a cross-sectional conjoint experiment in Spain and Italy |
| title_short | Attributes influencing parental decision-making to receive the Tdap vaccine to reduce the risk of pertussis transmission to their newborn – outcome of a cross-sectional conjoint experiment in Spain and Italy |
| title_sort | attributes influencing parental decision making to receive the tdap vaccine to reduce the risk of pertussis transmission to their newborn outcome of a cross sectional conjoint experiment in spain and italy |
| topic | pertussis vaccination cocooning spain italy adaptive choice-based conjoint questionnaire adaptive discrete-choice experiment preferences sawtooth software survey |
| url | http://dx.doi.org/10.1080/21645515.2019.1571890 |
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