Serum resistin and lipid profile in primigravida females with and without preeclampsia: an analytical cross-sectional study
Objective: To measure and compare the serum levels of resistin and lipid profile parameters in primigravida females with and without preeclampsia. Method: The analytical cross-sectional study was conducted at the Department of Physiology and Cell Biology, University of Health Sciences, Lahore, Pa...
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| Format: | Article |
| Language: | English |
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Pakistan Medical Association
2023-12-01
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| Series: | Journal of the Pakistan Medical Association |
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| Online Access: | https://ojs.jpma.org.pk/index.php/public_html/article/view/8218 |
| _version_ | 1797370861598015488 |
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| author | Mehwish Rana Mohsin Ali Cheema Rida Ajmal khan Asia Kanwal Arshia Mobeen Rana Khalid Parvez Lone |
| author_facet | Mehwish Rana Mohsin Ali Cheema Rida Ajmal khan Asia Kanwal Arshia Mobeen Rana Khalid Parvez Lone |
| author_sort | Mehwish Rana |
| collection | DOAJ |
| description |
Objective: To measure and compare the serum levels of resistin and lipid profile parameters in primigravida females with and without preeclampsia.
Method: The analytical cross-sectional study was conducted at the Department of Physiology and Cell Biology, University of Health Sciences, Lahore, Pakistan, from 2018 to 2020, and comprised primigravida females having gestational age 30-36 weeks. Those with preeclampsia constituted group 1, while normotensive females constituted group 2. All the participants were subjected to detailed history and general physical examination. Serum resistin levels were measured by enzyme-linked immunosorbent assay, and lipid profile parameters were measured using the colorimetric method. Data was analysed using SPSS 20.
Results: Of the 80 women, 40(50percent) were in group 1 with mean age 23.07±2.10 years and mean gestation age 33.45±2.30 weeks. There were 40(50percent) women in group 2 with mean age 23.02±2.11 years and mean gestational age 34.45±1.75 weeks. Mean serum resistin was significantly higher in group 1 compared to group 2 (p 0.02). Mean levels of lipid parameters were significantly different between the groups (p 0.05).
Conclusion: Preeclampsia was found to be associated with higher levels of resistin and lipid parameters compared to normal pregnancy.
Keywords: Pre-eclampsia, Resistin, Hypertension, Pregnancy outcome, Primigravida.
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| first_indexed | 2024-03-08T18:11:27Z |
| format | Article |
| id | doaj.art-5e3a6c4fc13441c39e35b9cb7add59bb |
| institution | Directory Open Access Journal |
| issn | 0030-9982 |
| language | English |
| last_indexed | 2024-03-08T18:11:27Z |
| publishDate | 2023-12-01 |
| publisher | Pakistan Medical Association |
| record_format | Article |
| series | Journal of the Pakistan Medical Association |
| spelling | doaj.art-5e3a6c4fc13441c39e35b9cb7add59bb2024-01-01T05:21:25ZengPakistan Medical AssociationJournal of the Pakistan Medical Association0030-99822023-12-0174110.47391/JPMA.8218Serum resistin and lipid profile in primigravida females with and without preeclampsia: an analytical cross-sectional studyMehwish Rana0Mohsin Ali Cheema1Rida Ajmal khan2Asia Kanwal3Arshia Mobeen Rana4Khalid Parvez Lone5Department of Physiology, Abu Umara Medical and Dental College, The Green International University, Lahore, PakistanDepartment of Physiology, Abu Umara Medical and Dental College, The Green International University, Lahore, PakistanDepartment of Physiology, Abu Umara Medical and Dental College, The Green International University, Lahore, PakistanDepartment of Physiology, Shalamar Medical and Dental College, Lahore, PakistanDepartment of Biochemistry, Allama Iqbal Medical College, Lahore, PakistanDepartment of Physiology, University of Health Sciences, Lahore, Pakistan Objective: To measure and compare the serum levels of resistin and lipid profile parameters in primigravida females with and without preeclampsia. Method: The analytical cross-sectional study was conducted at the Department of Physiology and Cell Biology, University of Health Sciences, Lahore, Pakistan, from 2018 to 2020, and comprised primigravida females having gestational age 30-36 weeks. Those with preeclampsia constituted group 1, while normotensive females constituted group 2. All the participants were subjected to detailed history and general physical examination. Serum resistin levels were measured by enzyme-linked immunosorbent assay, and lipid profile parameters were measured using the colorimetric method. Data was analysed using SPSS 20. Results: Of the 80 women, 40(50percent) were in group 1 with mean age 23.07±2.10 years and mean gestation age 33.45±2.30 weeks. There were 40(50percent) women in group 2 with mean age 23.02±2.11 years and mean gestational age 34.45±1.75 weeks. Mean serum resistin was significantly higher in group 1 compared to group 2 (p 0.02). Mean levels of lipid parameters were significantly different between the groups (p 0.05). Conclusion: Preeclampsia was found to be associated with higher levels of resistin and lipid parameters compared to normal pregnancy. Keywords: Pre-eclampsia, Resistin, Hypertension, Pregnancy outcome, Primigravida. https://ojs.jpma.org.pk/index.php/public_html/article/view/8218Pre-eclampsiaResistinHypertensionPregnancy outcomePrimigravida |
| spellingShingle | Mehwish Rana Mohsin Ali Cheema Rida Ajmal khan Asia Kanwal Arshia Mobeen Rana Khalid Parvez Lone Serum resistin and lipid profile in primigravida females with and without preeclampsia: an analytical cross-sectional study Journal of the Pakistan Medical Association Pre-eclampsia Resistin Hypertension Pregnancy outcome Primigravida |
| title | Serum resistin and lipid profile in primigravida females with and without preeclampsia: an analytical cross-sectional study |
| title_full | Serum resistin and lipid profile in primigravida females with and without preeclampsia: an analytical cross-sectional study |
| title_fullStr | Serum resistin and lipid profile in primigravida females with and without preeclampsia: an analytical cross-sectional study |
| title_full_unstemmed | Serum resistin and lipid profile in primigravida females with and without preeclampsia: an analytical cross-sectional study |
| title_short | Serum resistin and lipid profile in primigravida females with and without preeclampsia: an analytical cross-sectional study |
| title_sort | serum resistin and lipid profile in primigravida females with and without preeclampsia an analytical cross sectional study |
| topic | Pre-eclampsia Resistin Hypertension Pregnancy outcome Primigravida |
| url | https://ojs.jpma.org.pk/index.php/public_html/article/view/8218 |
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