Mitochondrial deoxyguanosine kinase is required for female fertility in mice

Mitochondrial deoxyguanosine kinase is required for female fertility in mice

Mitochondrial homeostasis plays a pivotal role in oocyte maturation and embryonic development. Deoxyguanosine kinase (DGUOK) is a nucleoside kinase that salvages purine nucleosides in mitochondria and is critical for mitochondrial DNA repli...

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Bibliographic Details
Main Authors: Gao Yake, Dong Rui, Yan Jiacong, Chen Huicheng, Sang Lei, Yao Xinyi, Fan Die, Wang Xin, Zuo Xiaoyuan, Zhang Xu, Yang Shengyu, Wu Ze, Sun Jianwei
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2024-02-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
DGUOK
infertility
mitochondria
nucleoside salvage pathway
oocyte maturation
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024003

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