Dietary Protein to Carbohydrate Ratio and Caloric Restriction: Comparing Metabolic Outcomes in Mice
Both caloric restriction (CR) and low-protein, high-carbohydrate (LPHC) ad-libitum-fed diets increase lifespan and improve metabolic parameters such as insulin, glucose, and blood lipids. Severe CR, however, is unsustainable for most people; therefore, it is important to determine whether manipulati...
Main Authors: | Samantha M. Solon-Biet, Sarah J. Mitchell, Sean C.P. Coogan, Victoria C. Cogger, Rahul Gokarn, Aisling C. McMahon, David Raubenheimer, Rafael de Cabo, Stephen J. Simpson, David G. Le Couteur |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-06-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124715005057 |
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