Comparison of microbiological assay and HPLC-UV for determination of fluconazole in capsules

Comparison of microbiological assay and HPLC-UV for determination of fluconazole in capsules

The development of a specific agar diffusion bioassay for the quantitative determination of fluconazole formulated in capsules was carried out using a strain of Candida albicans ATCC 18804 as the test organism. A prospective validation of the method showed adequate linearity (r²=0.9995), precision (...

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Bibliographic Details
Main Authors:	Kelly Marques Queiroz, Maria-Luiza Martins Silva, Nathália Duque Prado, Paulo Marcelo Andrade Lima, Rosiane Dias Lopes Diniz, Isabela Costa César, Gerson Antônio Pianetti, Daniel Assis Santos
Format:	Article
Language:	English
Published:	Universidade de São Paulo 2009-12-01
Series:	Brazilian Journal of Pharmaceutical Sciences
Subjects:	Fluconazol Ensaio microbiológico Cromatografia líquida de alta eficiência Fluconazole Microbiological assay High performance liquid chromatography
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000400012

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