Myeloperoxidase inhibition may protect against endothelial glycocalyx shedding induced by COVID-19 plasma

Myeloperoxidase inhibition may protect against endothelial glycocalyx shedding induced by COVID-19 plasma

Abstract Background SARS-CoV-2, the causative agent of COVID-19, is a threat to public health. Evidence suggests increased neutrophil activation and endothelial glycocalyx (EG) damage are independently associated with severe COVID-19. Here, we hypothesised that an increased level of blood neutrophil...

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Bibliographic Details
Main Authors: Andrew Teo, Louisa L. Y. Chan, Christine Cheung, Po Ying Chia, Sean Wei Xiang Ong, Siew Wai Fong, Lisa F. P. Ng, Laurent Renia, David Chien Lye, Barnaby Edward Young, Tsin Wen Yeo
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-023-00293-x

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