Comparison of ONT and CCS sequencing technologies on the polyploid genome of a medicinal plant showed that high error rate of ONT reads are not suitable for self-correction

Comparison of ONT and CCS sequencing technologies on the polyploid genome of a medicinal plant showed that high error rate of ONT reads are not suitable for self-correction

Abstract Background Many medicinal plants are known for their complex genomes with high ploidy, heterozygosity, and repetitive content which pose severe challenges for genome sequencing of those species. Long reads from Oxford nanopore sequencing technology (ONT) or Pacific Biosciences Single Molecu...

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Bibliographic Details
Main Authors: Peng Zeng, Zunzhe Tian, Yuwei Han, Weixiong Zhang, Tinggan Zhou, Yingmei Peng, Hao Hu, Jing Cai
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Chinese Medicine
Subjects:
ONT-based assembly
Allotetraploid
Veratrum dahuricum
Low-quality sequences
Homozygous variants
Online Access:https://doi.org/10.1186/s13020-022-00644-1

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