KDELC2 Upregulates Glioblastoma Angiogenesis via Reactive Oxygen Species Activation and Tumor-Associated Macrophage Proliferation

KDELC2 Upregulates Glioblastoma Angiogenesis via Reactive Oxygen Species Activation and Tumor-Associated Macrophage Proliferation

Glioblastoma is notorious for its rapid progression and neovascularization. In this study, it was found that KDEL (Lys-Asp-Glu-Leu) containing 2 (KDELC2) stimulated vasculogenic factor expression and induced human umbilical vein endothelial cell (HUVEC) proliferation. The NLRP3 inflammasome and auto...

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Bibliographic Details
Main Authors: Yu-Ling Tsai, Ying Chen, Ying-Chuan Chen, Wen-Chiuan Tsai
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Antioxidants
Subjects:
KDELC2
glioblastoma
angiogenesis
ROS
TAM
ER stress
Online Access:https://www.mdpi.com/2076-3921/12/4/923

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