Recent Strategies to Develop Conjugated Polymers for Detection and Therapeutics
The infectious diseases resulting from pathogenic microbes are highly contagious and the source of infection is difficult to control, which seriously endangers life and public health safety. Although the emergence of antibiotics has a good therapeutic effect in the early stage, the massive abuse of...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Polymers |
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| Online Access: | https://www.mdpi.com/2073-4360/15/17/3570 |
| _version_ | 1797581983126126592 |
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| author | Yutong Li Ruilian Qi Xiaoyu Wang Huanxiang Yuan |
| author_facet | Yutong Li Ruilian Qi Xiaoyu Wang Huanxiang Yuan |
| author_sort | Yutong Li |
| collection | DOAJ |
| description | The infectious diseases resulting from pathogenic microbes are highly contagious and the source of infection is difficult to control, which seriously endangers life and public health safety. Although the emergence of antibiotics has a good therapeutic effect in the early stage, the massive abuse of antibiotics has brought about the evolution of pathogens with drug resistance, which has gradually weakened the lethality and availability of antibiotics. Cancer is a more serious disease than pathogenic bacteria infection, which also threatens human life and health. Traditional treatment methods have limitations such as easy recurrence, poor prognosis, many side effects, and high toxicity. These two issues have led to the exploration and development of novel therapeutic agents (such as conjugated polymers) and therapeutic strategies (such as phototherapy) to avoid the increase of drug resistance and toxic side effects. As a class of organic polymer biological functional materials with excellent photoelectric properties, Conjugated polymers (CPs) have been extensively investigated in biomedical fields, such as the detection and treatment of pathogens and tumors due to their advantages of easy modification and functionalization, good biocompatibility and low cost. A rare comprehensive overview of CPs-based detection and treatment applications has been reported. This paper reviews the design strategies and research status of CPs used in biomedicine in recent years, introduces and discusses the latest progress of their application in the detection and treatment of pathogenic microorganisms and tumors according to different detection or treatment methods, as well as the limitations and potential challenges in prospective exploration. |
| first_indexed | 2024-03-10T23:14:19Z |
| format | Article |
| id | doaj.art-5e537e239ed3442f83cc846ff37ac177 |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-10T23:14:19Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-5e537e239ed3442f83cc846ff37ac1772023-11-19T08:43:28ZengMDPI AGPolymers2073-43602023-08-011517357010.3390/polym15173570Recent Strategies to Develop Conjugated Polymers for Detection and TherapeuticsYutong Li0Ruilian Qi1Xiaoyu Wang2Huanxiang Yuan3Department of Chemistry, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing 100048, ChinaDepartment of Chemistry, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing 100048, ChinaSchool of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, ChinaDepartment of Chemistry, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing 100048, ChinaThe infectious diseases resulting from pathogenic microbes are highly contagious and the source of infection is difficult to control, which seriously endangers life and public health safety. Although the emergence of antibiotics has a good therapeutic effect in the early stage, the massive abuse of antibiotics has brought about the evolution of pathogens with drug resistance, which has gradually weakened the lethality and availability of antibiotics. Cancer is a more serious disease than pathogenic bacteria infection, which also threatens human life and health. Traditional treatment methods have limitations such as easy recurrence, poor prognosis, many side effects, and high toxicity. These two issues have led to the exploration and development of novel therapeutic agents (such as conjugated polymers) and therapeutic strategies (such as phototherapy) to avoid the increase of drug resistance and toxic side effects. As a class of organic polymer biological functional materials with excellent photoelectric properties, Conjugated polymers (CPs) have been extensively investigated in biomedical fields, such as the detection and treatment of pathogens and tumors due to their advantages of easy modification and functionalization, good biocompatibility and low cost. A rare comprehensive overview of CPs-based detection and treatment applications has been reported. This paper reviews the design strategies and research status of CPs used in biomedicine in recent years, introduces and discusses the latest progress of their application in the detection and treatment of pathogenic microorganisms and tumors according to different detection or treatment methods, as well as the limitations and potential challenges in prospective exploration.https://www.mdpi.com/2073-4360/15/17/3570conjugated polymerspathogenic infectionscancerdetectiontherapy |
| spellingShingle | Yutong Li Ruilian Qi Xiaoyu Wang Huanxiang Yuan Recent Strategies to Develop Conjugated Polymers for Detection and Therapeutics Polymers conjugated polymers pathogenic infections cancer detection therapy |
| title | Recent Strategies to Develop Conjugated Polymers for Detection and Therapeutics |
| title_full | Recent Strategies to Develop Conjugated Polymers for Detection and Therapeutics |
| title_fullStr | Recent Strategies to Develop Conjugated Polymers for Detection and Therapeutics |
| title_full_unstemmed | Recent Strategies to Develop Conjugated Polymers for Detection and Therapeutics |
| title_short | Recent Strategies to Develop Conjugated Polymers for Detection and Therapeutics |
| title_sort | recent strategies to develop conjugated polymers for detection and therapeutics |
| topic | conjugated polymers pathogenic infections cancer detection therapy |
| url | https://www.mdpi.com/2073-4360/15/17/3570 |
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