Role of 18F-FDG PET/CT in evaluation of recently diagnosed breast cancer patients
Abstract Background Breast cancer is the most frequent malignant disease in women and usually affects people of all ages, races, socioeconomic classes, and geographic locations. Once breast cancer is diagnosed, tumor staging should be assessed precisely before treatment and prognosis could be determ...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-08-01
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| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43055-022-00866-1 |
| _version_ | 1811215503637610496 |
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| author | Ayat Mahmoud Kamal Omnia Ahmed Kamal Hossam Moussa Sakr Susan Adil Ali |
| author_facet | Ayat Mahmoud Kamal Omnia Ahmed Kamal Hossam Moussa Sakr Susan Adil Ali |
| author_sort | Ayat Mahmoud Kamal |
| collection | DOAJ |
| description | Abstract Background Breast cancer is the most frequent malignant disease in women and usually affects people of all ages, races, socioeconomic classes, and geographic locations. Once breast cancer is diagnosed, tumor staging should be assessed precisely before treatment and prognosis could be determined. The purpose of this study was to determine the diagnostic usefulness of PET/CT in the initial assessment of patients with newly diagnosed breast cancer who were referred for tumor staging, pre-therapeutic or preoperative evaluation. Results In the examined 50 patients, PET/CT has higher sensitivity and accuracy compared to CT alone (reaching 100% for PET/CT and 96% for CT) in detecting malignant breast lesions, regional and distant nodal deposits as well as distant deposits, with subsequent upstaging in two patients. Conclusions 18F-FDG PET/CT is a single valuable technique that detects metastatic illness in newly diagnosed breast cancer patients in an efficient, accurate, and noninvasive manner, resulting in modification of the initial staging, which in turn reflected on the patients' therapeutic plans. |
| first_indexed | 2024-04-12T06:23:41Z |
| format | Article |
| id | doaj.art-5e54eef8219d407683132e22374c2975 |
| institution | Directory Open Access Journal |
| issn | 2090-4762 |
| language | English |
| last_indexed | 2024-04-12T06:23:41Z |
| publishDate | 2022-08-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj.art-5e54eef8219d407683132e22374c29752022-12-22T03:44:13ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine2090-47622022-08-0153111010.1186/s43055-022-00866-1Role of 18F-FDG PET/CT in evaluation of recently diagnosed breast cancer patientsAyat Mahmoud Kamal0Omnia Ahmed Kamal1Hossam Moussa Sakr2Susan Adil Ali3Ain Shams UniversityRadiodiagnosis Department, Ain Shams UniversityRadiodiagnosis Department, Ain Shams UniversityRadiodiagnosis Department, Ain Shams UniversityAbstract Background Breast cancer is the most frequent malignant disease in women and usually affects people of all ages, races, socioeconomic classes, and geographic locations. Once breast cancer is diagnosed, tumor staging should be assessed precisely before treatment and prognosis could be determined. The purpose of this study was to determine the diagnostic usefulness of PET/CT in the initial assessment of patients with newly diagnosed breast cancer who were referred for tumor staging, pre-therapeutic or preoperative evaluation. Results In the examined 50 patients, PET/CT has higher sensitivity and accuracy compared to CT alone (reaching 100% for PET/CT and 96% for CT) in detecting malignant breast lesions, regional and distant nodal deposits as well as distant deposits, with subsequent upstaging in two patients. Conclusions 18F-FDG PET/CT is a single valuable technique that detects metastatic illness in newly diagnosed breast cancer patients in an efficient, accurate, and noninvasive manner, resulting in modification of the initial staging, which in turn reflected on the patients' therapeutic plans.https://doi.org/10.1186/s43055-022-00866-1Breast cancerPositron emission tomographyComputed tomography |
| spellingShingle | Ayat Mahmoud Kamal Omnia Ahmed Kamal Hossam Moussa Sakr Susan Adil Ali Role of 18F-FDG PET/CT in evaluation of recently diagnosed breast cancer patients The Egyptian Journal of Radiology and Nuclear Medicine Breast cancer Positron emission tomography Computed tomography |
| title | Role of 18F-FDG PET/CT in evaluation of recently diagnosed breast cancer patients |
| title_full | Role of 18F-FDG PET/CT in evaluation of recently diagnosed breast cancer patients |
| title_fullStr | Role of 18F-FDG PET/CT in evaluation of recently diagnosed breast cancer patients |
| title_full_unstemmed | Role of 18F-FDG PET/CT in evaluation of recently diagnosed breast cancer patients |
| title_short | Role of 18F-FDG PET/CT in evaluation of recently diagnosed breast cancer patients |
| title_sort | role of 18f fdg pet ct in evaluation of recently diagnosed breast cancer patients |
| topic | Breast cancer Positron emission tomography Computed tomography |
| url | https://doi.org/10.1186/s43055-022-00866-1 |
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