Chronic persistent HHV‐6B infection after sulfasalazine‐induced DRESS with demonstration of HHV‐6 encoded small noncoding RNAs (sncRNAs) in Crohn’s‐like colitis: Case report
Abstract A sulfasalazine‐induced DRESS (Drug Reactivation with Eosinophilia and Systemic Symptoms) was complicated by a Crohn's‐like colitis. We demonstrated HHV‐6 reactivation with presence of HHV‐6 DNA and small noncoding RNA in colonic lesions. This observation confirms the major role of HHV...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-02-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.3680 |
| _version_ | 1831525017909723136 |
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| author | Vincent Descamps Agnès Gautheret‐Dejean Anne‐Laure Pelletier Pascale Bonnafous Lydia Deschamps Bhupesh K. Prusty |
| author_facet | Vincent Descamps Agnès Gautheret‐Dejean Anne‐Laure Pelletier Pascale Bonnafous Lydia Deschamps Bhupesh K. Prusty |
| author_sort | Vincent Descamps |
| collection | DOAJ |
| description | Abstract A sulfasalazine‐induced DRESS (Drug Reactivation with Eosinophilia and Systemic Symptoms) was complicated by a Crohn's‐like colitis. We demonstrated HHV‐6 reactivation with presence of HHV‐6 DNA and small noncoding RNA in colonic lesions. This observation confirms the major role of HHV‐6 reactivation in DRESS manifestations and the importance of looking for HHV‐6 reactivation in DRESS. |
| first_indexed | 2024-12-16T15:43:11Z |
| format | Article |
| id | doaj.art-5e5703d3f0604962ac22b4f3dbb00aee |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-12-16T15:43:11Z |
| publishDate | 2021-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-5e5703d3f0604962ac22b4f3dbb00aee2022-12-21T22:25:55ZengWileyClinical Case Reports2050-09042021-02-019284184410.1002/ccr3.3680Chronic persistent HHV‐6B infection after sulfasalazine‐induced DRESS with demonstration of HHV‐6 encoded small noncoding RNAs (sncRNAs) in Crohn’s‐like colitis: Case reportVincent Descamps0Agnès Gautheret‐Dejean1Anne‐Laure Pelletier2Pascale Bonnafous3Lydia Deschamps4Bhupesh K. Prusty5Department of Dermatology Bichat Hospital APHP ParisParis 7 University Paris FranceDepartment of Virology Pitié‐Salpêtrière Hospital APHP Paris FranceDepartment of Gastroenterology Bichat Hospital APHP ParisParis 7 University Paris FranceINSERM, IPLESP, THERAVIR team Sorbonne Université Paris FranceDepartment of Pathology Bichat Hospital APHP ParisParis 7 University Paris FranceInstitute for Virology and Immunobiology University of Wuerzburg Wuerzburg GermanyAbstract A sulfasalazine‐induced DRESS (Drug Reactivation with Eosinophilia and Systemic Symptoms) was complicated by a Crohn's‐like colitis. We demonstrated HHV‐6 reactivation with presence of HHV‐6 DNA and small noncoding RNA in colonic lesions. This observation confirms the major role of HHV‐6 reactivation in DRESS manifestations and the importance of looking for HHV‐6 reactivation in DRESS.https://doi.org/10.1002/ccr3.3680Crohn's diseasedrug reaction with eosinophilia and systemic symptomsdrug‐induced hypersensitivity syndromehuman herpesvirus 6B |
| spellingShingle | Vincent Descamps Agnès Gautheret‐Dejean Anne‐Laure Pelletier Pascale Bonnafous Lydia Deschamps Bhupesh K. Prusty Chronic persistent HHV‐6B infection after sulfasalazine‐induced DRESS with demonstration of HHV‐6 encoded small noncoding RNAs (sncRNAs) in Crohn’s‐like colitis: Case report Clinical Case Reports Crohn's disease drug reaction with eosinophilia and systemic symptoms drug‐induced hypersensitivity syndrome human herpesvirus 6B |
| title | Chronic persistent HHV‐6B infection after sulfasalazine‐induced DRESS with demonstration of HHV‐6 encoded small noncoding RNAs (sncRNAs) in Crohn’s‐like colitis: Case report |
| title_full | Chronic persistent HHV‐6B infection after sulfasalazine‐induced DRESS with demonstration of HHV‐6 encoded small noncoding RNAs (sncRNAs) in Crohn’s‐like colitis: Case report |
| title_fullStr | Chronic persistent HHV‐6B infection after sulfasalazine‐induced DRESS with demonstration of HHV‐6 encoded small noncoding RNAs (sncRNAs) in Crohn’s‐like colitis: Case report |
| title_full_unstemmed | Chronic persistent HHV‐6B infection after sulfasalazine‐induced DRESS with demonstration of HHV‐6 encoded small noncoding RNAs (sncRNAs) in Crohn’s‐like colitis: Case report |
| title_short | Chronic persistent HHV‐6B infection after sulfasalazine‐induced DRESS with demonstration of HHV‐6 encoded small noncoding RNAs (sncRNAs) in Crohn’s‐like colitis: Case report |
| title_sort | chronic persistent hhv 6b infection after sulfasalazine induced dress with demonstration of hhv 6 encoded small noncoding rnas sncrnas in crohn s like colitis case report |
| topic | Crohn's disease drug reaction with eosinophilia and systemic symptoms drug‐induced hypersensitivity syndrome human herpesvirus 6B |
| url | https://doi.org/10.1002/ccr3.3680 |
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