Cerenkov Radiation: A Multi-functional Approach for Biological Sciences
Cerenkov radiation (CR) has been used in various biological research fields, which has aroused lots of attention in recent years. Combining optical imaging instruments and most of nuclear medicine imaging or radiotherapy probes, the CR was developed as a new imaging modality for biology studies, cal...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2014-02-01
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| Series: | Frontiers in Physics |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphy.2014.00004/full |
| _version_ | 1819140530363170816 |
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| author | Xiaowei eMa Xiaowei eMa Jing eWang Zhen eCheng |
| author_facet | Xiaowei eMa Xiaowei eMa Jing eWang Zhen eCheng |
| author_sort | Xiaowei eMa |
| collection | DOAJ |
| description | Cerenkov radiation (CR) has been used in various biological research fields, which has aroused lots of attention in recent years. Combining optical imaging instruments and most of nuclear medicine imaging or radiotherapy probes, the CR was developed as a new imaging modality for biology studies, called Cerenkov luminescence imaging (CLI). On the other hand, it was novelly used as an internal excitation source to activate some fluorophores for energy transfer imaging. However, it also has some shortages such as relatively weak luminescence intensity and low penetration in tissue. Thus some scientific groups demonstrated to optimize the CLI and demonstrated it to three-dimension tomography. In this article, we elaborate on its principle, history, and applications and discuss a number of directions for technical improvements. Then concluded some advantages and shortages of CR and discuss some prospects of it. |
| first_indexed | 2024-12-22T11:40:01Z |
| format | Article |
| id | doaj.art-5e589ce1ff8d48e2ae93e566c76f4f9e |
| institution | Directory Open Access Journal |
| issn | 2296-424X |
| language | English |
| last_indexed | 2024-12-22T11:40:01Z |
| publishDate | 2014-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physics |
| spelling | doaj.art-5e589ce1ff8d48e2ae93e566c76f4f9e2022-12-21T18:27:18ZengFrontiers Media S.A.Frontiers in Physics2296-424X2014-02-01210.3389/fphy.2014.0000469907Cerenkov Radiation: A Multi-functional Approach for Biological SciencesXiaowei eMa0Xiaowei eMa1Jing eWang2Zhen eCheng3Stanford UniversityXijing HospitalXijing HospitalStanford UniversityCerenkov radiation (CR) has been used in various biological research fields, which has aroused lots of attention in recent years. Combining optical imaging instruments and most of nuclear medicine imaging or radiotherapy probes, the CR was developed as a new imaging modality for biology studies, called Cerenkov luminescence imaging (CLI). On the other hand, it was novelly used as an internal excitation source to activate some fluorophores for energy transfer imaging. However, it also has some shortages such as relatively weak luminescence intensity and low penetration in tissue. Thus some scientific groups demonstrated to optimize the CLI and demonstrated it to three-dimension tomography. In this article, we elaborate on its principle, history, and applications and discuss a number of directions for technical improvements. Then concluded some advantages and shortages of CR and discuss some prospects of it.http://journal.frontiersin.org/Journal/10.3389/fphy.2014.00004/fullMolecular Imagingoptical imagingPETSPECTCerenkov Radiation |
| spellingShingle | Xiaowei eMa Xiaowei eMa Jing eWang Zhen eCheng Cerenkov Radiation: A Multi-functional Approach for Biological Sciences Frontiers in Physics Molecular Imaging optical imaging PET SPECT Cerenkov Radiation |
| title | Cerenkov Radiation: A Multi-functional Approach for Biological Sciences |
| title_full | Cerenkov Radiation: A Multi-functional Approach for Biological Sciences |
| title_fullStr | Cerenkov Radiation: A Multi-functional Approach for Biological Sciences |
| title_full_unstemmed | Cerenkov Radiation: A Multi-functional Approach for Biological Sciences |
| title_short | Cerenkov Radiation: A Multi-functional Approach for Biological Sciences |
| title_sort | cerenkov radiation a multi functional approach for biological sciences |
| topic | Molecular Imaging optical imaging PET SPECT Cerenkov Radiation |
| url | http://journal.frontiersin.org/Journal/10.3389/fphy.2014.00004/full |
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