GABA, glutamate and excitatory-inhibitory ratios measured using short-TE STEAM MRS at 7-Tesla: Effects of macromolecule basis sets and baseline parameters

GABA, glutamate and excitatory-inhibitory ratios measured using short-TE STEAM MRS at 7-Tesla: Effects of macromolecule basis sets and baseline parameters

Rationale and objectives: Macromolecules (MMs) affect the precision and accuracy of neurochemical quantification in magnetic resonance spectroscopy. A measured MM basis is increasingly used in LCModel analysis combined with a spline baseline, whose stiffness is controlled by a parameter named DKNTMN...

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Bibliographic Details
Main Authors: Tomohisa Okada, Hideto Kuribayashi, Yuta Urushibata, Koji Fujimoto, Thai Akasaka, Ravi Teja Seethamraju, Sinyeob Ahn, Tadashi Isa
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Heliyon
Subjects:
Gamma-aminobutyric acid
Glutamate
Excitatory-inhibitory ratio
Stimulated echo acquisition mode
Magnetic resonance spectroscopy
7-Tesla
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023055652

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