An Applied Research in Properties and Clinical Application of Bone Marrow of Mesenchymal Stem Cells
In the last 15 years, there has been a significant increase in the number of researchers interested in studying Mesenchymal Stem Cells (MSCs). MSCs are self-renewing, heterogenic, and multipotent cells that have multi-lineage potential to differentiate not only in to cell types of mesodermal origin...
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| Format: | Article |
| Language: | English |
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Fasa University of Medical Sciences
2015-11-01
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| Series: | Journal of Advanced Biomedical Sciences |
| Subjects: | |
| Online Access: | http://jabs.fums.ac.ir/article-1-756-en.pdf |
| _version_ | 1797679623522222080 |
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| author | Zahra Barzkar Mohammadhosein Karimi Zohre Makoolati Gholamreza Kaka Majid Naghdi |
| author_facet | Zahra Barzkar Mohammadhosein Karimi Zohre Makoolati Gholamreza Kaka Majid Naghdi |
| author_sort | Zahra Barzkar |
| collection | DOAJ |
| description | In the last 15 years, there has been a significant increase in the number of researchers interested in studying Mesenchymal Stem Cells (MSCs). MSCs are self-renewing, heterogenic, and multipotent cells that have multi-lineage potential to differentiate not only in to cell types of mesodermal origin but also other various cell lineage MSCs migrate to inflammatory tissues and apply immunosuppressive effects. The usages of these cells as diagnostic tool, secretor of some growth factors and cytokines, gene expresser of engineered cells, and other characteristics such as relatively easy preparation and proliferation, add to the attraction of these cells. Scientists suggest that the transplantation of these cells is a proper alternative for treatment of some incurable illnesses of bone, heart, skin, and liver such as diabetes. However, these kinds of treatment, not clearly associated with the definitive remedial results, are going on in an additive manner. Introducing stem cells with their miracle properties as a predictive precipitance and their curative potential in the recent years, led to many questions, concerns, and expectations regarding this newly proposed therapeutic method. Nowadays, knowing the true extent of the curative effect of these cells, especially in some tissues more clearly reduces concerns and makes expectations more rational like other treatments. |
| first_indexed | 2024-03-11T23:17:29Z |
| format | Article |
| id | doaj.art-5e5eb1d6787f4b8b94973ff1c3f97ed5 |
| institution | Directory Open Access Journal |
| issn | 2228-5105 2783-1523 |
| language | English |
| last_indexed | 2024-03-11T23:17:29Z |
| publishDate | 2015-11-01 |
| publisher | Fasa University of Medical Sciences |
| record_format | Article |
| series | Journal of Advanced Biomedical Sciences |
| spelling | doaj.art-5e5eb1d6787f4b8b94973ff1c3f97ed52023-09-20T21:20:34ZengFasa University of Medical SciencesJournal of Advanced Biomedical Sciences2228-51052783-15232015-11-0153306322An Applied Research in Properties and Clinical Application of Bone Marrow of Mesenchymal Stem CellsZahra Barzkar0Mohammadhosein Karimi1Zohre Makoolati2Gholamreza Kaka3Majid Naghdi4 Noncommunicable diseases research center, Fasa University of Medical Sciences, Fasa, Iran Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran Department of Anatomical sciences, Fasa University of Medical Sciences, Fasa, Iran Neuroscience research centre, Baqiyatallah University of Medical Sciences, Tehran, Iran. Department of Anatomical sciences, Fasa University of Medical Sciences, Fasa, Iran In the last 15 years, there has been a significant increase in the number of researchers interested in studying Mesenchymal Stem Cells (MSCs). MSCs are self-renewing, heterogenic, and multipotent cells that have multi-lineage potential to differentiate not only in to cell types of mesodermal origin but also other various cell lineage MSCs migrate to inflammatory tissues and apply immunosuppressive effects. The usages of these cells as diagnostic tool, secretor of some growth factors and cytokines, gene expresser of engineered cells, and other characteristics such as relatively easy preparation and proliferation, add to the attraction of these cells. Scientists suggest that the transplantation of these cells is a proper alternative for treatment of some incurable illnesses of bone, heart, skin, and liver such as diabetes. However, these kinds of treatment, not clearly associated with the definitive remedial results, are going on in an additive manner. Introducing stem cells with their miracle properties as a predictive precipitance and their curative potential in the recent years, led to many questions, concerns, and expectations regarding this newly proposed therapeutic method. Nowadays, knowing the true extent of the curative effect of these cells, especially in some tissues more clearly reduces concerns and makes expectations more rational like other treatments.http://jabs.fums.ac.ir/article-1-756-en.pdfmesenchymal stem cellsstudiesfactstherapeutic ability |
| spellingShingle | Zahra Barzkar Mohammadhosein Karimi Zohre Makoolati Gholamreza Kaka Majid Naghdi An Applied Research in Properties and Clinical Application of Bone Marrow of Mesenchymal Stem Cells Journal of Advanced Biomedical Sciences mesenchymal stem cells studies facts therapeutic ability |
| title | An Applied Research in Properties and Clinical Application of Bone Marrow of Mesenchymal Stem Cells |
| title_full | An Applied Research in Properties and Clinical Application of Bone Marrow of Mesenchymal Stem Cells |
| title_fullStr | An Applied Research in Properties and Clinical Application of Bone Marrow of Mesenchymal Stem Cells |
| title_full_unstemmed | An Applied Research in Properties and Clinical Application of Bone Marrow of Mesenchymal Stem Cells |
| title_short | An Applied Research in Properties and Clinical Application of Bone Marrow of Mesenchymal Stem Cells |
| title_sort | applied research in properties and clinical application of bone marrow of mesenchymal stem cells |
| topic | mesenchymal stem cells studies facts therapeutic ability |
| url | http://jabs.fums.ac.ir/article-1-756-en.pdf |
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