Platelet functions in healthy persons with genetic polymorphisms gpia(с807т), gpiiia(т1565с), gpipa(с434т), p2ry12(н1/н2), selp(-g1087a) platelet receptions
Allele and genotype frequencies of 5 polymorphisms were studied in healthy population in Transbaikalian region. High percent of spontaneous and inductive aggregation were observed in subjects with three or more mutant allele (р < 0,05). These subjects developed maximum radius of aggregates only i...
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| Format: | Article |
| Language: | Russian |
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Scientific Сentre for Family Health and Human Reproduction Problems
2013-11-01
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| Series: | Acta Biomedica Scientifica |
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| Online Access: | https://www.actabiomedica.ru/jour/article/view/1682 |
| _version_ | 1797237482202333184 |
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| author | N. N. Strambovskaya |
| author_facet | N. N. Strambovskaya |
| author_sort | N. N. Strambovskaya |
| collection | DOAJ |
| description | Allele and genotype frequencies of 5 polymorphisms were studied in healthy population in Transbaikalian region. High percent of spontaneous and inductive aggregation were observed in subjects with three or more mutant allele (р < 0,05). These subjects developed maximum radius of aggregates only in spontaneous -1,7 ± 0,4 opt.un. (р < 0,05) and collagen-induced aggregation - 7,6 ± 2,5 opt.un. (р < 0,05). |
| first_indexed | 2024-03-08T12:19:56Z |
| format | Article |
| id | doaj.art-5e612c53b9fe4dfa8e13ae32ad3c7f29 |
| institution | Directory Open Access Journal |
| issn | 2541-9420 2587-9596 |
| language | Russian |
| last_indexed | 2024-04-24T17:20:27Z |
| publishDate | 2013-11-01 |
| publisher | Scientific Сentre for Family Health and Human Reproduction Problems |
| record_format | Article |
| series | Acta Biomedica Scientifica |
| spelling | doaj.art-5e612c53b9fe4dfa8e13ae32ad3c7f292024-03-28T07:49:12ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962013-11-010665701628Platelet functions in healthy persons with genetic polymorphisms gpia(с807т), gpiiia(т1565с), gpipa(с434т), p2ry12(н1/н2), selp(-g1087a) platelet receptionsN. N. Strambovskaya0State Budgetary Educational Institution of Higher Professional Education «Chita State Medical Academy», the Ministry of Healthcare, Russian FederationAllele and genotype frequencies of 5 polymorphisms were studied in healthy population in Transbaikalian region. High percent of spontaneous and inductive aggregation were observed in subjects with three or more mutant allele (р < 0,05). These subjects developed maximum radius of aggregates only in spontaneous -1,7 ± 0,4 opt.un. (р < 0,05) and collagen-induced aggregation - 7,6 ± 2,5 opt.un. (р < 0,05).https://www.actabiomedica.ru/jour/article/view/1682plateletsaggregate of plateletplatelet receptionsgene polymorphismpopulation genetics |
| spellingShingle | N. N. Strambovskaya Platelet functions in healthy persons with genetic polymorphisms gpia(с807т), gpiiia(т1565с), gpipa(с434т), p2ry12(н1/н2), selp(-g1087a) platelet receptions Acta Biomedica Scientifica platelets aggregate of platelet platelet receptions gene polymorphism population genetics |
| title | Platelet functions in healthy persons with genetic polymorphisms gpia(с807т), gpiiia(т1565с), gpipa(с434т), p2ry12(н1/н2), selp(-g1087a) platelet receptions |
| title_full | Platelet functions in healthy persons with genetic polymorphisms gpia(с807т), gpiiia(т1565с), gpipa(с434т), p2ry12(н1/н2), selp(-g1087a) platelet receptions |
| title_fullStr | Platelet functions in healthy persons with genetic polymorphisms gpia(с807т), gpiiia(т1565с), gpipa(с434т), p2ry12(н1/н2), selp(-g1087a) platelet receptions |
| title_full_unstemmed | Platelet functions in healthy persons with genetic polymorphisms gpia(с807т), gpiiia(т1565с), gpipa(с434т), p2ry12(н1/н2), selp(-g1087a) platelet receptions |
| title_short | Platelet functions in healthy persons with genetic polymorphisms gpia(с807т), gpiiia(т1565с), gpipa(с434т), p2ry12(н1/н2), selp(-g1087a) platelet receptions |
| title_sort | platelet functions in healthy persons with genetic polymorphisms gpia с807т gpiiia т1565с gpipa с434т p2ry12 н1 н2 selp g1087a platelet receptions |
| topic | platelets aggregate of platelet platelet receptions gene polymorphism population genetics |
| url | https://www.actabiomedica.ru/jour/article/view/1682 |
| work_keys_str_mv | AT nnstrambovskaya plateletfunctionsinhealthypersonswithgeneticpolymorphismsgpias807tgpiiiat1565sgpipas434tp2ry12n1n2selpg1087aplateletreceptions |