Interstitial pneumonia with autoimmune features: A case series and overview
The topic of interstitial pneumonia with autoimmune features (IPAF) is a research classification proposed by the European Respiratory Society/American Thoracic Society Task Force: this includes patients with idiopathic interstitial pneumonia (IIP) and clinical features, suggesting an underlying auto...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-01-01
|
| Series: | Respiratory Medicine Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007121000125 |
| _version_ | 1818742080182157312 |
|---|---|
| author | Ana Luísa Fernandes Jorge Ferreira Inês Neves |
| author_facet | Ana Luísa Fernandes Jorge Ferreira Inês Neves |
| author_sort | Ana Luísa Fernandes |
| collection | DOAJ |
| description | The topic of interstitial pneumonia with autoimmune features (IPAF) is a research classification proposed by the European Respiratory Society/American Thoracic Society Task Force: this includes patients with idiopathic interstitial pneumonia (IIP) and clinical features, suggesting an underlying autoimmune process, but who do not meet established criteria for a connective tissue disease (CTD). We aimed to perform a detailed characterization of clinical, serological, and radiological features for our patients with IPAF criteria. Six patients were included, and a comprehensive description of these cases revealed a heterogeneous group in terms of clinical and treatment options. In most patients, it was possible to identify other features and disorders with an autoimmune “background,” which may support the inclusion of these patients in the IPAF classification. No deaths or significant decline in lung function occurred, and thus no definitive diagnosis of CTD could be found over 35 months of median follow-up. Therefore, IPAF is a recent concept, with many questions still open in regard to its usage in the ILD field. |
| first_indexed | 2024-12-18T02:06:50Z |
| format | Article |
| id | doaj.art-5e614010d7014af39162b54d1479a0cd |
| institution | Directory Open Access Journal |
| issn | 2213-0071 |
| language | English |
| last_indexed | 2024-12-18T02:06:50Z |
| publishDate | 2021-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj.art-5e614010d7014af39162b54d1479a0cd2022-12-21T21:24:34ZengElsevierRespiratory Medicine Case Reports2213-00712021-01-0132101350Interstitial pneumonia with autoimmune features: A case series and overviewAna Luísa Fernandes0Jorge Ferreira1Inês Neves2Corresponding author. , Rua Dr. Eduardo Torres / 4464-513, Senhora da Hora, Matosinhos, Portugal.; Pulmonology Department, Hospital Pedro Hispano, Matosinhos, PortugalPulmonology Department, Hospital Pedro Hispano, Matosinhos, PortugalPulmonology Department, Hospital Pedro Hispano, Matosinhos, PortugalThe topic of interstitial pneumonia with autoimmune features (IPAF) is a research classification proposed by the European Respiratory Society/American Thoracic Society Task Force: this includes patients with idiopathic interstitial pneumonia (IIP) and clinical features, suggesting an underlying autoimmune process, but who do not meet established criteria for a connective tissue disease (CTD). We aimed to perform a detailed characterization of clinical, serological, and radiological features for our patients with IPAF criteria. Six patients were included, and a comprehensive description of these cases revealed a heterogeneous group in terms of clinical and treatment options. In most patients, it was possible to identify other features and disorders with an autoimmune “background,” which may support the inclusion of these patients in the IPAF classification. No deaths or significant decline in lung function occurred, and thus no definitive diagnosis of CTD could be found over 35 months of median follow-up. Therefore, IPAF is a recent concept, with many questions still open in regard to its usage in the ILD field.http://www.sciencedirect.com/science/article/pii/S2213007121000125Interstitial pneumonia with autoimmune featuresInterstitial lung diseaseConnective tissue disease |
| spellingShingle | Ana Luísa Fernandes Jorge Ferreira Inês Neves Interstitial pneumonia with autoimmune features: A case series and overview Respiratory Medicine Case Reports Interstitial pneumonia with autoimmune features Interstitial lung disease Connective tissue disease |
| title | Interstitial pneumonia with autoimmune features: A case series and overview |
| title_full | Interstitial pneumonia with autoimmune features: A case series and overview |
| title_fullStr | Interstitial pneumonia with autoimmune features: A case series and overview |
| title_full_unstemmed | Interstitial pneumonia with autoimmune features: A case series and overview |
| title_short | Interstitial pneumonia with autoimmune features: A case series and overview |
| title_sort | interstitial pneumonia with autoimmune features a case series and overview |
| topic | Interstitial pneumonia with autoimmune features Interstitial lung disease Connective tissue disease |
| url | http://www.sciencedirect.com/science/article/pii/S2213007121000125 |
| work_keys_str_mv | AT analuisafernandes interstitialpneumoniawithautoimmunefeaturesacaseseriesandoverview AT jorgeferreira interstitialpneumoniawithautoimmunefeaturesacaseseriesandoverview AT inesneves interstitialpneumoniawithautoimmunefeaturesacaseseriesandoverview |