Clinicopathological characteristics of rectal multiple neuroendocrine neoplasms and literature review
Abstract Background There are only a few epidemiological reports available for reference. The clinicopathological features are not clear, so there is no consensus on treating rectal multiple neuroendocrine neoplasms. This study aims to summarize the clinicopathological characteristics and preliminar...
| Những tác giả chính: | , , , , , , |
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| Định dạng: | Bài viết |
| Ngôn ngữ: | English |
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BMC
2023-06-01
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| Loạt: | BMC Surgery |
| Những chủ đề: | |
| Truy cập trực tuyến: | https://doi.org/10.1186/s12893-023-02050-2 |
| _version_ | 1827933933008846848 |
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| author | Xiuli Zheng Mingli Wu Shengmian Li Limian Er Huiyan Deng Shuo Guo Zhihuan Liu |
| author_facet | Xiuli Zheng Mingli Wu Shengmian Li Limian Er Huiyan Deng Shuo Guo Zhihuan Liu |
| author_sort | Xiuli Zheng |
| collection | DOAJ |
| description | Abstract Background There are only a few epidemiological reports available for reference. The clinicopathological features are not clear, so there is no consensus on treating rectal multiple neuroendocrine neoplasms. This study aims to summarize the clinicopathological characteristics and preliminarily discuss the clinical diagnosis and treatment of rectal multiple neuroendocrine neoplasms. Methods This study retrospectively analyzed rectal neuroendocrine neoplasm patients diagnosed and treated at the Fourth Hospital of Hebei Medical University from February 2007 to May 2021. The clinicopathological characteristics of rectal multiple neuroendocrine neoplasms were summarized and analyzed in combination with 14 studies on rectal multiple neuroendocrine neoplasms. Results The incidence of RM-NENs accounted for 3.8% of all R-NENs in this study. The number of tumors varied to some extent, the size of tumors was basically no more than 10 mm, and there were more G1 grade tumors. In the analysis of 46 cases with known lymph node metastasis, the difference in lymph node metastasis rate between the number of tumors < 8 and ≥ 8 was statistically significant (p = 0.002). Conclusions The incidence of rectal multiple neuroendocrine neoplasms accounted for 3.8% of all rectal neuroendocrine neoplasms. For rectal multiple neuroendocrine neoplasms, the lymph node metastasis rate was higher when the number of tumors was ≥ 8. The influence of the number of tumors on lymph node metastasis should be considered in the selection of treatment. |
| first_indexed | 2024-03-13T07:31:30Z |
| format | Article |
| id | doaj.art-5e687156d3e84ed19976ff729fdc417b |
| institution | Directory Open Access Journal |
| issn | 1471-2482 |
| language | English |
| last_indexed | 2024-03-13T07:31:30Z |
| publishDate | 2023-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Surgery |
| spelling | doaj.art-5e687156d3e84ed19976ff729fdc417b2023-06-04T11:05:25ZengBMCBMC Surgery1471-24822023-06-012311710.1186/s12893-023-02050-2Clinicopathological characteristics of rectal multiple neuroendocrine neoplasms and literature reviewXiuli Zheng0Mingli Wu1Shengmian Li2Limian Er3Huiyan Deng4Shuo Guo5Zhihuan Liu6Department of Endoscopy, Fourth Hospital of Hebei Medical UniversityDepartment of Endoscopy, Fourth Hospital of Hebei Medical UniversityDepartment of Gastroenterology, Fourth Hospital of Hebei Medical UniversityDepartment of Endoscopy, Fourth Hospital of Hebei Medical UniversityDepartment of Pathology, Fourth Hospital of Hebei Medical UniversityDepartment of Endoscopy, Fourth Hospital of Hebei Medical UniversityDepartment of Endoscopy, Fourth Hospital of Hebei Medical UniversityAbstract Background There are only a few epidemiological reports available for reference. The clinicopathological features are not clear, so there is no consensus on treating rectal multiple neuroendocrine neoplasms. This study aims to summarize the clinicopathological characteristics and preliminarily discuss the clinical diagnosis and treatment of rectal multiple neuroendocrine neoplasms. Methods This study retrospectively analyzed rectal neuroendocrine neoplasm patients diagnosed and treated at the Fourth Hospital of Hebei Medical University from February 2007 to May 2021. The clinicopathological characteristics of rectal multiple neuroendocrine neoplasms were summarized and analyzed in combination with 14 studies on rectal multiple neuroendocrine neoplasms. Results The incidence of RM-NENs accounted for 3.8% of all R-NENs in this study. The number of tumors varied to some extent, the size of tumors was basically no more than 10 mm, and there were more G1 grade tumors. In the analysis of 46 cases with known lymph node metastasis, the difference in lymph node metastasis rate between the number of tumors < 8 and ≥ 8 was statistically significant (p = 0.002). Conclusions The incidence of rectal multiple neuroendocrine neoplasms accounted for 3.8% of all rectal neuroendocrine neoplasms. For rectal multiple neuroendocrine neoplasms, the lymph node metastasis rate was higher when the number of tumors was ≥ 8. The influence of the number of tumors on lymph node metastasis should be considered in the selection of treatment.https://doi.org/10.1186/s12893-023-02050-2Rectal neuroendocrine neoplasmRectal multiple neuroendocrine neoplasmsLymph node metastasis |
| spellingShingle | Xiuli Zheng Mingli Wu Shengmian Li Limian Er Huiyan Deng Shuo Guo Zhihuan Liu Clinicopathological characteristics of rectal multiple neuroendocrine neoplasms and literature review BMC Surgery Rectal neuroendocrine neoplasm Rectal multiple neuroendocrine neoplasms Lymph node metastasis |
| title | Clinicopathological characteristics of rectal multiple neuroendocrine neoplasms and literature review |
| title_full | Clinicopathological characteristics of rectal multiple neuroendocrine neoplasms and literature review |
| title_fullStr | Clinicopathological characteristics of rectal multiple neuroendocrine neoplasms and literature review |
| title_full_unstemmed | Clinicopathological characteristics of rectal multiple neuroendocrine neoplasms and literature review |
| title_short | Clinicopathological characteristics of rectal multiple neuroendocrine neoplasms and literature review |
| title_sort | clinicopathological characteristics of rectal multiple neuroendocrine neoplasms and literature review |
| topic | Rectal neuroendocrine neoplasm Rectal multiple neuroendocrine neoplasms Lymph node metastasis |
| url | https://doi.org/10.1186/s12893-023-02050-2 |
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