Impact of Laboratory-Adapted Intracellular <i>Trypanosoma cruzi</i> Strains on the Activity Profiles of Compounds with Anti-<i>T. cruzi</i> Activity

Chagas disease is caused by infection with the protozoan parasite, <i>Trypanosoma cruzi</i>. The disease causes ~12,000 deaths annually and is one of the world’s 20 neglected tropical diseases, as defined by the World Health Organisation. The drug discovery pipeline for Chagas disease cu...

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Bibliographic Details
Main Authors: Melissa L. Sykes, Emily K. Kennedy, Vicky M. Avery
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/11/2/476