A temporary indwelling intravascular aphaeretic system for in vivo enrichment of circulating tumor cells
Ex vivo methods of circulating tumor cell (CTC) isolation use small blood volumes, limiting sensitivity and introducing analytical inaccuracies. The authors describe a proof-of-concept study of an in vivo aphaeresis system that continuously collects CTCs from a peripheral vein over several hours.
Main Authors: | Tae Hyun Kim, Yang Wang, C. Ryan Oliver, Douglas H. Thamm, Laura Cooling, Costanza Paoletti, Kaylee J. Smith, Sunitha Nagrath, Daniel F. Hayes |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2019-04-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-09439-9 |
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