A Report of a patient with Diarrhea: Pseudomembranous Colitis
Background and Objectives: Pseudomembranous colitis is an advanced form of infection with clostridium difficile, which damage epithelial cells following colonization in the intestine and production of toxins A and B. Diarrhea is the most common clinical manifestation caused by C. difficile, which in...
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| Format: | Article |
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Qom University of Medical Sciences
2016-04-01
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| Series: | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum |
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| Online Access: | http://journal.muq.ac.ir/article-1-442-en.html |
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| author | Ahmad Hormati Mohammad Reza Ghadir Seyed Saeed Sarkeshikian Mahdi Mahdi Pezeshki Modarres Faezeh Alemi Mahdieh Ghoddoosi |
| author_facet | Ahmad Hormati Mohammad Reza Ghadir Seyed Saeed Sarkeshikian Mahdi Mahdi Pezeshki Modarres Faezeh Alemi Mahdieh Ghoddoosi |
| author_sort | Ahmad Hormati |
| collection | DOAJ |
| description | Background and Objectives: Pseudomembranous colitis is an advanced form of infection with clostridium difficile, which damage epithelial cells following colonization in the intestine and production of toxins A and B. Diarrhea is the most common clinical manifestation caused by C. difficile, which in these cases, blood is never observed macroscopically in the stool. Antibiotic exposure is the main risk factor for this infection and is especially associated with ampicillin, clindamycine, and 2nd and 3rd generation cephalosporins, such as ceftriaxone, cefotaxime, and ceftazidime. To confirm the diagnosis of infection, assessment of the microorganism toxins in the stool by PCR as well as observation of pseudomembrane in colonoscopy, was performed. In this article, a case of an old patient with diarrhea (pseudomembranous colitis) was presented in this article.
Case Report: The patient is an 85-year-old man with signs of weakness, fatigue, fever and chills, and non-productive cough and diagnosis of pneumonia underwent antibiotic therapy, and in the course of treatment, he demonstrated massive watery diarrhea. Laboratory colonoscopy findings was indicative of infection with C. difficile. |
| first_indexed | 2024-12-14T00:25:16Z |
| format | Article |
| id | doaj.art-5e6fea15bd734eafa10744eb4ce44929 |
| institution | Directory Open Access Journal |
| issn | 1735-7799 2008-1375 |
| language | fas |
| last_indexed | 2024-12-14T00:25:16Z |
| publishDate | 2016-04-01 |
| publisher | Qom University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum |
| spelling | doaj.art-5e6fea15bd734eafa10744eb4ce449292022-12-21T23:25:04ZfasQom University of Medical SciencesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum1735-77992008-13752016-04-011018893A Report of a patient with Diarrhea: Pseudomembranous ColitisAhmad Hormati0Mohammad Reza Ghadir1Seyed Saeed Sarkeshikian2Mahdi Mahdi Pezeshki Modarres3Faezeh Alemi4Mahdieh Ghoddoosi5 Gastroenterology & Hepatology Research Center, Qom University of Medical Sciences, Qom, Iran. 1Gastroenterology & Hepatology Research Center, Qom University of Medical Sciences, Qom, Iran. 1Gastroenterology & Hepatology Research Center, Qom University of Medical Sciences, Qom, Iran. 2Qom University of Medical Sciences, Qom, Iran. Faculty of Medicine, Qom University of Medical Sciences, Qom, Iran. Qom University of Medical Sciences, Qom, Iran. Background and Objectives: Pseudomembranous colitis is an advanced form of infection with clostridium difficile, which damage epithelial cells following colonization in the intestine and production of toxins A and B. Diarrhea is the most common clinical manifestation caused by C. difficile, which in these cases, blood is never observed macroscopically in the stool. Antibiotic exposure is the main risk factor for this infection and is especially associated with ampicillin, clindamycine, and 2nd and 3rd generation cephalosporins, such as ceftriaxone, cefotaxime, and ceftazidime. To confirm the diagnosis of infection, assessment of the microorganism toxins in the stool by PCR as well as observation of pseudomembrane in colonoscopy, was performed. In this article, a case of an old patient with diarrhea (pseudomembranous colitis) was presented in this article. Case Report: The patient is an 85-year-old man with signs of weakness, fatigue, fever and chills, and non-productive cough and diagnosis of pneumonia underwent antibiotic therapy, and in the course of treatment, he demonstrated massive watery diarrhea. Laboratory colonoscopy findings was indicative of infection with C. difficile.http://journal.muq.ac.ir/article-1-442-en.htmlclostridium difficileenterocolitispseudomembranousdiarrhea |
| spellingShingle | Ahmad Hormati Mohammad Reza Ghadir Seyed Saeed Sarkeshikian Mahdi Mahdi Pezeshki Modarres Faezeh Alemi Mahdieh Ghoddoosi A Report of a patient with Diarrhea: Pseudomembranous Colitis Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum clostridium difficile enterocolitis pseudomembranous diarrhea |
| title | A Report of a patient with Diarrhea: Pseudomembranous Colitis |
| title_full | A Report of a patient with Diarrhea: Pseudomembranous Colitis |
| title_fullStr | A Report of a patient with Diarrhea: Pseudomembranous Colitis |
| title_full_unstemmed | A Report of a patient with Diarrhea: Pseudomembranous Colitis |
| title_short | A Report of a patient with Diarrhea: Pseudomembranous Colitis |
| title_sort | report of a patient with diarrhea pseudomembranous colitis |
| topic | clostridium difficile enterocolitis pseudomembranous diarrhea |
| url | http://journal.muq.ac.ir/article-1-442-en.html |
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