NLRX1 Enhances Glutamate Uptake and Inhibits Glutamate Release by Astrocytes

NLRX1 Enhances Glutamate Uptake and Inhibits Glutamate Release by Astrocytes

Uptake of glutamate from the extracellular space and glutamate release to neurons are two major processes conducted by astrocytes in the central nervous system (CNS) that protect against glutamate excitotoxicity and strengthen neuronal firing, respectively. During inflammatory conditions in the CNS,...

Full description

Bibliographic Details
Main Authors: Shaimaa Mahmoud, Marjan Gharagozloo, Camille Simard, Abdelaziz Amrani, Denis Gris
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cells
Subjects:
NLRX1
astrocytes
CNS
glutamate uptake
glutamate release
excitotoxicity
Online Access:https://www.mdpi.com/2073-4409/8/5/400

Similar Items

Similar Items