Heterotopic Pancreas in the Duodenum Diagnosed after Laparoscopic Biopsy
Heterotopic pancreas is defined as the presence of ectopic pancreatic tissue outside boundaries of the pancreas without vascular and duct system connection with the pancreas. Ectopic locations are mostly found anywhere in the gastrointestinal tract such as the stomach (24–38%), the duodenum (9–36%),...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2022-09-01
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| Series: | Case Reports in Gastroenterology |
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| Online Access: | https://www.karger.com/Article/FullText/526135 |
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| author | Ngoc Trinh Thi Pham Anh Nguyet Thi Nguyen Minh Tri Thi Vo Minh Duc Pham |
| author_facet | Ngoc Trinh Thi Pham Anh Nguyet Thi Nguyen Minh Tri Thi Vo Minh Duc Pham |
| author_sort | Ngoc Trinh Thi Pham |
| collection | DOAJ |
| description | Heterotopic pancreas is defined as the presence of ectopic pancreatic tissue outside boundaries of the pancreas without vascular and duct system connection with the pancreas. Ectopic locations are mostly found anywhere in the gastrointestinal tract such as the stomach (24–38%), the duodenum (9–36%), and the jejunum (0.5–27%). Clinical manifestations are not specific, vague, and misdiagnosed another digestive disease. Most cases are incidentally detected by histological examination of specimens resected for different pathologies during endoscopy, surgery, or even autopsy. We report a case of a 31-year-old man who admitted to the hospital with the reason of epigastric pain for 3 days. Clinical examination showed mild epigastric tenderness. The past medical history of patient was unremarkable. A submucosal lesion was observed in the first part of the duodenum during endoscopy. Computed tomography and endoscopic ultrasonography findings were suspected to be heterotopic pancreatic tissue. After laparoscopic surgery for biopsy, it was histologically confirmed duodenal ectopic pancreas. It is difficult to differentiate gastrointestinal pancreatic heterotopia from gastrointestinal stromal tumors, leiomyoma, or lymphomas by using endoscopy because ectopic tissue is mostly located in the submucosal layer. In addition, rare cases of ectopic pancreatic tissue transform malignancy. Surgical treatment should be considered to take adequate tissue samples for biopsy or resect the lesions in symptomatic patients. Duodenal pancreatic heterotopia is an uncommon congenital malformation and most patients are asymptomatic. Histological examination is essential to exclude malignant lesions and to have an appropriate treatment. |
| first_indexed | 2024-04-11T17:20:07Z |
| format | Article |
| id | doaj.art-5e77144555754e17ad85433a1e528876 |
| institution | Directory Open Access Journal |
| issn | 1662-0631 |
| language | English |
| last_indexed | 2024-04-11T17:20:07Z |
| publishDate | 2022-09-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Gastroenterology |
| spelling | doaj.art-5e77144555754e17ad85433a1e5288762022-12-22T04:12:30ZengKarger PublishersCase Reports in Gastroenterology1662-06312022-09-0116354655110.1159/000526135526135Heterotopic Pancreas in the Duodenum Diagnosed after Laparoscopic BiopsyNgoc Trinh Thi Pham0Anh Nguyet Thi Nguyen1Minh Tri Thi Vo2Minh Duc Pham3School of Medicine and Pharmacy, The University of Danang, Da Nang, VietnamSchool of Medicine and Pharmacy, The University of Danang, Da Nang, VietnamSchool of Medicine and Pharmacy, The University of Danang, Da Nang, VietnamDepartment of Surgery, Hue University of Medicine and Pharmacy, Hue University, Hue, VietnamHeterotopic pancreas is defined as the presence of ectopic pancreatic tissue outside boundaries of the pancreas without vascular and duct system connection with the pancreas. Ectopic locations are mostly found anywhere in the gastrointestinal tract such as the stomach (24–38%), the duodenum (9–36%), and the jejunum (0.5–27%). Clinical manifestations are not specific, vague, and misdiagnosed another digestive disease. Most cases are incidentally detected by histological examination of specimens resected for different pathologies during endoscopy, surgery, or even autopsy. We report a case of a 31-year-old man who admitted to the hospital with the reason of epigastric pain for 3 days. Clinical examination showed mild epigastric tenderness. The past medical history of patient was unremarkable. A submucosal lesion was observed in the first part of the duodenum during endoscopy. Computed tomography and endoscopic ultrasonography findings were suspected to be heterotopic pancreatic tissue. After laparoscopic surgery for biopsy, it was histologically confirmed duodenal ectopic pancreas. It is difficult to differentiate gastrointestinal pancreatic heterotopia from gastrointestinal stromal tumors, leiomyoma, or lymphomas by using endoscopy because ectopic tissue is mostly located in the submucosal layer. In addition, rare cases of ectopic pancreatic tissue transform malignancy. Surgical treatment should be considered to take adequate tissue samples for biopsy or resect the lesions in symptomatic patients. Duodenal pancreatic heterotopia is an uncommon congenital malformation and most patients are asymptomatic. Histological examination is essential to exclude malignant lesions and to have an appropriate treatment.https://www.karger.com/Article/FullText/526135ectopic pancreasheterotopic pancreasduodenal ectopic pancreas |
| spellingShingle | Ngoc Trinh Thi Pham Anh Nguyet Thi Nguyen Minh Tri Thi Vo Minh Duc Pham Heterotopic Pancreas in the Duodenum Diagnosed after Laparoscopic Biopsy Case Reports in Gastroenterology ectopic pancreas heterotopic pancreas duodenal ectopic pancreas |
| title | Heterotopic Pancreas in the Duodenum Diagnosed after Laparoscopic Biopsy |
| title_full | Heterotopic Pancreas in the Duodenum Diagnosed after Laparoscopic Biopsy |
| title_fullStr | Heterotopic Pancreas in the Duodenum Diagnosed after Laparoscopic Biopsy |
| title_full_unstemmed | Heterotopic Pancreas in the Duodenum Diagnosed after Laparoscopic Biopsy |
| title_short | Heterotopic Pancreas in the Duodenum Diagnosed after Laparoscopic Biopsy |
| title_sort | heterotopic pancreas in the duodenum diagnosed after laparoscopic biopsy |
| topic | ectopic pancreas heterotopic pancreas duodenal ectopic pancreas |
| url | https://www.karger.com/Article/FullText/526135 |
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