Seroprevalence of transfusion-transmitted infections among blood donors in a tertiary care hospital in Puducherry

Introduction: Although significant strides have happened in making blood transfusions safe, with each transfusion, there is a chance to transmit transfusion-transmitted infections (TTI), namely viral, bacterial, parasitic, and prions. The primary objective of this study was to assess the seroprevale...

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Main Authors: Jayasree Cherukat, Rajendra Kulkarni, Abhishekh Basavarajegowda
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Journal of Primary Care Specialties
Subjects:
Online Access:http://www.jpcsonline.org/article.asp?issn=2772-3615;year=2022;volume=3;issue=1;spage=8;epage=12;aulast=Cherukat
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author Jayasree Cherukat
Rajendra Kulkarni
Abhishekh Basavarajegowda
author_facet Jayasree Cherukat
Rajendra Kulkarni
Abhishekh Basavarajegowda
author_sort Jayasree Cherukat
collection DOAJ
description Introduction: Although significant strides have happened in making blood transfusions safe, with each transfusion, there is a chance to transmit transfusion-transmitted infections (TTI), namely viral, bacterial, parasitic, and prions. The primary objective of this study was to assess the seroprevalence of the five mandatorily to be tested TTI's in India among blood donors at our center. Methodology: This was a cross-sectional observational study conducted in the Department of Transfusion Medicine, a tertiary care hospital in Puducherry, from August 2015 to February 2017. Enzyme-linked immunosorbent assay was done for HIV, HCV, HBsAg/hepatitis B surface antigen, and rapid plasma reagin test was done for syphilis. Rapid card testing was done for malaria. Results: There were a total of 28,380 donors during the study period. In the present study, the overall seroprevalence of TTI's was 3.06%. The individual seropositivity rates were 0.30% for HIV, 2.15% for HBsAg, 0.51% for HCV, and 0.08% for syphilis. There was no case of malaria diagnosed in the study period. Conclusion: The seroprevalence of TTI in Puducherry was similar to those reported elsewhere in the country. It was comparable to the national average with regard to HIV and HCV, higher for HBV and much lesser for syphilis.
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spelling doaj.art-5e77cdbfeda545989179ae721eaa45732022-12-22T01:49:29ZengWolters Kluwer Medknow PublicationsJournal of Primary Care Specialties2772-36152772-36232022-01-013181210.4103/jopcs.jopcs_2_21Seroprevalence of transfusion-transmitted infections among blood donors in a tertiary care hospital in PuducherryJayasree CherukatRajendra KulkarniAbhishekh BasavarajegowdaIntroduction: Although significant strides have happened in making blood transfusions safe, with each transfusion, there is a chance to transmit transfusion-transmitted infections (TTI), namely viral, bacterial, parasitic, and prions. The primary objective of this study was to assess the seroprevalence of the five mandatorily to be tested TTI's in India among blood donors at our center. Methodology: This was a cross-sectional observational study conducted in the Department of Transfusion Medicine, a tertiary care hospital in Puducherry, from August 2015 to February 2017. Enzyme-linked immunosorbent assay was done for HIV, HCV, HBsAg/hepatitis B surface antigen, and rapid plasma reagin test was done for syphilis. Rapid card testing was done for malaria. Results: There were a total of 28,380 donors during the study period. In the present study, the overall seroprevalence of TTI's was 3.06%. The individual seropositivity rates were 0.30% for HIV, 2.15% for HBsAg, 0.51% for HCV, and 0.08% for syphilis. There was no case of malaria diagnosed in the study period. Conclusion: The seroprevalence of TTI in Puducherry was similar to those reported elsewhere in the country. It was comparable to the national average with regard to HIV and HCV, higher for HBV and much lesser for syphilis.http://www.jpcsonline.org/article.asp?issn=2772-3615;year=2022;volume=3;issue=1;spage=8;epage=12;aulast=Cherukatpuducherryseroprevalencetransfusion-transmitted infections
spellingShingle Jayasree Cherukat
Rajendra Kulkarni
Abhishekh Basavarajegowda
Seroprevalence of transfusion-transmitted infections among blood donors in a tertiary care hospital in Puducherry
Journal of Primary Care Specialties
puducherry
seroprevalence
transfusion-transmitted infections
title Seroprevalence of transfusion-transmitted infections among blood donors in a tertiary care hospital in Puducherry
title_full Seroprevalence of transfusion-transmitted infections among blood donors in a tertiary care hospital in Puducherry
title_fullStr Seroprevalence of transfusion-transmitted infections among blood donors in a tertiary care hospital in Puducherry
title_full_unstemmed Seroprevalence of transfusion-transmitted infections among blood donors in a tertiary care hospital in Puducherry
title_short Seroprevalence of transfusion-transmitted infections among blood donors in a tertiary care hospital in Puducherry
title_sort seroprevalence of transfusion transmitted infections among blood donors in a tertiary care hospital in puducherry
topic puducherry
seroprevalence
transfusion-transmitted infections
url http://www.jpcsonline.org/article.asp?issn=2772-3615;year=2022;volume=3;issue=1;spage=8;epage=12;aulast=Cherukat
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AT rajendrakulkarni seroprevalenceoftransfusiontransmittedinfectionsamongblooddonorsinatertiarycarehospitalinpuducherry
AT abhishekhbasavarajegowda seroprevalenceoftransfusiontransmittedinfectionsamongblooddonorsinatertiarycarehospitalinpuducherry