Effect of Supplemental Oxygen on von Willebrand Factor Activity and Ristocetin Cofactor Activity in Patients at Risk for Cardiovascular Complications Undergoing Moderate-to High-Risk Major Noncardiac Surgery—A Secondary Analysis of a Randomized Trial

Effect of Supplemental Oxygen on von Willebrand Factor Activity and Ristocetin Cofactor Activity in Patients at Risk for Cardiovascular Complications Undergoing Moderate-to High-Risk Major Noncardiac Surgery—A Secondary Analysis of a Randomized Trial

Increased von Willebrand Factor (vWF) activity mediates platelet adhesion and might be a contributor to the development of thrombotic complications after surgery. Although in vitro studies have shown that hyperoxia induces endovascular damage, the effect of perioperative supplemental oxygen as a pos...

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Bibliographic Details
Main Authors: Katharina Horvath, Alexander Taschner, Nikolas Adamowitsch, Markus Falkner von Sonnenburg, Edith Fleischmann, Barbara Kabon, Melanie Fraunschiel, Christian Reiterer, Alexandra Graf
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Journal of Clinical Medicine
Subjects:
von Willebrand factor
ristocetin
endothelial demage
noncardiac surgery
Online Access:https://www.mdpi.com/2077-0383/12/3/1222

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