The “Inverse” Seasonal Blood Pressure Variability Phenotype
The seasonal blood pressure variability (BPV) is known to demonstrate a typical winter peak. Recently, more attention is paid to the opposite situation: the summer BP levels being higher than those in winter. This phenomenon is called inverse BPV. The present article summarizes recent data on this t...
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| Format: | Article |
| Language: | English |
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Столичная издательская компания
2021-07-01
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| Series: | Рациональная фармакотерапия в кардиологии |
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| Online Access: | https://www.rpcardio.online/jour/article/view/2511 |
| _version_ | 1797232084985577472 |
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| author | V. M. Gorbunov M. I. Smirnova Y. N. Koshelyaevskaya N. N. Panueva N. V. Furman P. V. Dolotovskaya |
| author_facet | V. M. Gorbunov M. I. Smirnova Y. N. Koshelyaevskaya N. N. Panueva N. V. Furman P. V. Dolotovskaya |
| author_sort | V. M. Gorbunov |
| collection | DOAJ |
| description | The seasonal blood pressure variability (BPV) is known to demonstrate a typical winter peak. Recently, more attention is paid to the opposite situation: the summer BP levels being higher than those in winter. This phenomenon is called inverse BPV. The present article summarizes recent data on this topic. The data of the HOMED-BP project, as well as the results of the original prospective study in 770 hypertensive patients from two Russian Federation regions (mean follow-up duration 6.4 years), were used. According to the preliminary knowledge, the prevalence of inverse BPV in hypertensive patients is relatively high (15-25%). This phenomenon is more typical for treated patients, particularly for those on combination therapy, and is associated with beta-blocker intake. Higher duration of hypertension and higher levels of some risk factors (smoking) characterize the patients with inverse BPV. According to the HOMED-BP data, patients with inverse BPV had the highest overall cardiovascular risk (hazard ratio in comparison with the reference group of “minimal” “normal” BPV was 3.07; p=0.004). In summary, inverse BPV is a potentially unfavorable BP phenotype. However, its reproducibility and prospective value deserve further investigation. The absolute magnitude of seasonal BPV in these patients, calculated using different BP measurement methods, warrants special attention. |
| first_indexed | 2024-03-08T14:01:01Z |
| format | Article |
| id | doaj.art-5e7f6a4e433b40a2986d766b5db966da |
| institution | Directory Open Access Journal |
| issn | 1819-6446 2225-3653 |
| language | English |
| last_indexed | 2024-04-24T15:54:40Z |
| publishDate | 2021-07-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj.art-5e7f6a4e433b40a2986d766b5db966da2024-04-01T07:43:41ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532021-07-0117347047510.20996/1819-6446-2021-06-131916The “Inverse” Seasonal Blood Pressure Variability PhenotypeV. M. Gorbunov0M. I. Smirnova1Y. N. Koshelyaevskaya2N. N. Panueva3N. V. Furman4P. V. Dolotovskaya5National Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineIvanovo State Medical AcademySaratov State Medical University named after V.I. RazumovskySaratov State Medical University named after V.I. RazumovskyThe seasonal blood pressure variability (BPV) is known to demonstrate a typical winter peak. Recently, more attention is paid to the opposite situation: the summer BP levels being higher than those in winter. This phenomenon is called inverse BPV. The present article summarizes recent data on this topic. The data of the HOMED-BP project, as well as the results of the original prospective study in 770 hypertensive patients from two Russian Federation regions (mean follow-up duration 6.4 years), were used. According to the preliminary knowledge, the prevalence of inverse BPV in hypertensive patients is relatively high (15-25%). This phenomenon is more typical for treated patients, particularly for those on combination therapy, and is associated with beta-blocker intake. Higher duration of hypertension and higher levels of some risk factors (smoking) characterize the patients with inverse BPV. According to the HOMED-BP data, patients with inverse BPV had the highest overall cardiovascular risk (hazard ratio in comparison with the reference group of “minimal” “normal” BPV was 3.07; p=0.004). In summary, inverse BPV is a potentially unfavorable BP phenotype. However, its reproducibility and prospective value deserve further investigation. The absolute magnitude of seasonal BPV in these patients, calculated using different BP measurement methods, warrants special attention.https://www.rpcardio.online/jour/article/view/2511blood pressure variabilityblood pressure phenotype“inverse” seasonal blood pressure variability |
| spellingShingle | V. M. Gorbunov M. I. Smirnova Y. N. Koshelyaevskaya N. N. Panueva N. V. Furman P. V. Dolotovskaya The “Inverse” Seasonal Blood Pressure Variability Phenotype Рациональная фармакотерапия в кардиологии blood pressure variability blood pressure phenotype “inverse” seasonal blood pressure variability |
| title | The “Inverse” Seasonal Blood Pressure Variability Phenotype |
| title_full | The “Inverse” Seasonal Blood Pressure Variability Phenotype |
| title_fullStr | The “Inverse” Seasonal Blood Pressure Variability Phenotype |
| title_full_unstemmed | The “Inverse” Seasonal Blood Pressure Variability Phenotype |
| title_short | The “Inverse” Seasonal Blood Pressure Variability Phenotype |
| title_sort | inverse seasonal blood pressure variability phenotype |
| topic | blood pressure variability blood pressure phenotype “inverse” seasonal blood pressure variability |
| url | https://www.rpcardio.online/jour/article/view/2511 |
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