Prolidase Stimulates Proliferation and Migration through Activation of the PI3K/Akt/mTOR Signaling Pathway in Human Keratinocytes

Prolidase Stimulates Proliferation and Migration through Activation of the PI3K/Akt/mTOR Signaling Pathway in Human Keratinocytes

Recent reports have indicated prolidase (PEPD) as a ligand of the epidermal growth factor receptor (EGFR). Since this receptor is involved in the promotion of cell proliferation, growth, and migration, we aimed to investigate whether prolidase may participate in wound healing in vitro. All experimen...

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Bibliographic Details
Main Authors: Magdalena Misiura, Weronika Baszanowska, Ilona Ościłowska, Jerzy Pałka, Wojciech Miltyk
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
prolidase
PEPD
EGFR
keratinocytes
wound healing
Online Access:https://www.mdpi.com/1422-0067/21/23/9243

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