Deciphering the molecular and cellular atlas of immune cells in septic patients with different bacterial infections

Deciphering the molecular and cellular atlas of immune cells in septic patients with different bacterial infections

Abstract Background Sepsis is a life-threatening organ dysfunction caused by abnormal immune responses to various, predominantly bacterial, infections. Different bacterial infections lead to substantial variation in disease manifestation and therapeutic strategies. However, the underlying cellular h...

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Bibliographic Details
Main Authors: Ping Sun, Mintian Cui, Jiongjie Jing, Fanyu Kong, Shixi Wang, Lunxian Tang, Junling Leng, Kun Chen
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Translational Medicine
Subjects:
Sepsis
Various bacterial infections
Multi-omics
Cellular heterogeneity
Stratified targeted therapies
Online Access:https://doi.org/10.1186/s12967-023-04631-4

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