Predictive score for clinical complications during intra-hospital transports of infants treated in a neonatal unit
OBJECTIVE: To develop and validate a predictive score for clinical complications during intra-hospital transport of infants treated in neonatal units. METHODS: This was a cross-sectional study nested in a prospective cohort of infants transported within a public university hospital from January 2001...
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| Format: | Article |
| Language: | English |
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Elsevier España
2011-01-01
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| Series: | Clinics |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011000400009 |
| _version_ | 1818522593670463488 |
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| author | Anna Luiza Pires Vieira Amélia Miyashiro Nunes dos Santos Mariana Kobayashi Okuyama Milton Harumi Miyoshi Maria Fernanda Branco de Almeida Ruth Guinsburg |
| author_facet | Anna Luiza Pires Vieira Amélia Miyashiro Nunes dos Santos Mariana Kobayashi Okuyama Milton Harumi Miyoshi Maria Fernanda Branco de Almeida Ruth Guinsburg |
| author_sort | Anna Luiza Pires Vieira |
| collection | DOAJ |
| description | OBJECTIVE: To develop and validate a predictive score for clinical complications during intra-hospital transport of infants treated in neonatal units. METHODS: This was a cross-sectional study nested in a prospective cohort of infants transported within a public university hospital from January 2001 to December 2008. Transports during even (n=301) and odd (n = 394) years were compared to develop and validate a predictive score. The points attributed to each score variable were derived from multiple logistic regression analysis. The predictive performance and the score calibration were analyzed by a receiver operating characteristic (ROC) curve and Hosmer-Lemeshow test, respectively. RESULTS: Infants with a mean gestational age of 35 + 4 weeks and a birth weight of 2457 + 841 g were studied. In the derivation cohort, clinical complications occurred in 74 (24.6%) transports. Logistic regression analysis identified five variables associated with these complications and assigned corresponding point values: gestation at birth [<28 weeks (6 pts); 28-34 weeks (3 pts); >34 weeks (2 pts)]; pre-transport temperature [<36.3°Cor >37°C(3pts); 36.3-37.0°C (2 pts)]; underlying pathological condition [CNS malformation (4 pts); other (2 pts)]; transport destination [surgery (5 pts); magnetic resonance or computed tomography imaging (3 pts); other (2 pts)]; and pre-transport respiratory support [mechanical ventilation (8 pts); supplemental oxygen (7 pts); no oxygen (2 pts)]. For the derivation and validation cohorts, the areas under the ROC curve were 0.770 and 0.712, respectively. Expected and observed frequencies of complications were similar between the two cohorts. CONCLUSION: The predictive score developed and validated in this study presented adequate discriminative power and calibration. This score can help identify infants at risk of clinical complications during intra-hospital transports. |
| first_indexed | 2024-12-11T05:35:21Z |
| format | Article |
| id | doaj.art-5e82a929b6a34c1b9bdbee3546845321 |
| institution | Directory Open Access Journal |
| issn | 1807-5932 1980-5322 |
| language | English |
| last_indexed | 2024-12-11T05:35:21Z |
| publishDate | 2011-01-01 |
| publisher | Elsevier España |
| record_format | Article |
| series | Clinics |
| spelling | doaj.art-5e82a929b6a34c1b9bdbee35468453212022-12-22T01:19:18ZengElsevier EspañaClinics1807-59321980-53222011-01-0166457357710.1590/S1807-59322011000400009Predictive score for clinical complications during intra-hospital transports of infants treated in a neonatal unitAnna Luiza Pires VieiraAmélia Miyashiro Nunes dos SantosMariana Kobayashi OkuyamaMilton Harumi MiyoshiMaria Fernanda Branco de AlmeidaRuth GuinsburgOBJECTIVE: To develop and validate a predictive score for clinical complications during intra-hospital transport of infants treated in neonatal units. METHODS: This was a cross-sectional study nested in a prospective cohort of infants transported within a public university hospital from January 2001 to December 2008. Transports during even (n=301) and odd (n = 394) years were compared to develop and validate a predictive score. The points attributed to each score variable were derived from multiple logistic regression analysis. The predictive performance and the score calibration were analyzed by a receiver operating characteristic (ROC) curve and Hosmer-Lemeshow test, respectively. RESULTS: Infants with a mean gestational age of 35 + 4 weeks and a birth weight of 2457 + 841 g were studied. In the derivation cohort, clinical complications occurred in 74 (24.6%) transports. Logistic regression analysis identified five variables associated with these complications and assigned corresponding point values: gestation at birth [<28 weeks (6 pts); 28-34 weeks (3 pts); >34 weeks (2 pts)]; pre-transport temperature [<36.3°Cor >37°C(3pts); 36.3-37.0°C (2 pts)]; underlying pathological condition [CNS malformation (4 pts); other (2 pts)]; transport destination [surgery (5 pts); magnetic resonance or computed tomography imaging (3 pts); other (2 pts)]; and pre-transport respiratory support [mechanical ventilation (8 pts); supplemental oxygen (7 pts); no oxygen (2 pts)]. For the derivation and validation cohorts, the areas under the ROC curve were 0.770 and 0.712, respectively. Expected and observed frequencies of complications were similar between the two cohorts. CONCLUSION: The predictive score developed and validated in this study presented adequate discriminative power and calibration. This score can help identify infants at risk of clinical complications during intra-hospital transports.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011000400009Risk indextransportation of patientsinfant newbornneonatal intensive care unitsrisk factors |
| spellingShingle | Anna Luiza Pires Vieira Amélia Miyashiro Nunes dos Santos Mariana Kobayashi Okuyama Milton Harumi Miyoshi Maria Fernanda Branco de Almeida Ruth Guinsburg Predictive score for clinical complications during intra-hospital transports of infants treated in a neonatal unit Clinics Risk index transportation of patients infant newborn neonatal intensive care units risk factors |
| title | Predictive score for clinical complications during intra-hospital transports of infants treated in a neonatal unit |
| title_full | Predictive score for clinical complications during intra-hospital transports of infants treated in a neonatal unit |
| title_fullStr | Predictive score for clinical complications during intra-hospital transports of infants treated in a neonatal unit |
| title_full_unstemmed | Predictive score for clinical complications during intra-hospital transports of infants treated in a neonatal unit |
| title_short | Predictive score for clinical complications during intra-hospital transports of infants treated in a neonatal unit |
| title_sort | predictive score for clinical complications during intra hospital transports of infants treated in a neonatal unit |
| topic | Risk index transportation of patients infant newborn neonatal intensive care units risk factors |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011000400009 |
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