Serum Proteomics Reveals Alterations in Protease Activity, Axon Guidance, and Visual Phototransduction Pathways in Infants With In Utero Exposure to Zika Virus Without Congenital Zika Syndrome

Serum Proteomics Reveals Alterations in Protease Activity, Axon Guidance, and Visual Phototransduction Pathways in Infants With In Utero Exposure to Zika Virus Without Congenital Zika Syndrome

In 2015, ZIKV infection attracted international attention during an epidemic in the Americas, when neurological disorders were reported in infants who had their mothers exposed to ZIKV during pregnancy. World Health Organization (WHO) epidemiological data show that 5 to 15% of neonates exposed to ZI...

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Bibliographic Details
Main Authors: Janaina Macedo-da-Silva, Lívia Rosa-Fernandes, Raquel Hora Barbosa, Claudia B. Angeli, Fabiana Rabe Carvalho, Renata Artimos de Oliveira Vianna, Paulo C. Carvalho, Martin R. Larsen, Claudete Araújo Cardoso, Giuseppe Palmisano
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Zika virus
late abnormalities
serum proteomics
mass spectrometry
biomarker
Congenital Zika Syndrome
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2020.577819/full

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