Analysis of regulating activities of 5′-epiequisetin on proliferation, apoptosis, and migration of prostate cancer cells in vitro and in vivo

Analysis of regulating activities of 5′-epiequisetin on proliferation, apoptosis, and migration of prostate cancer cells in vitro and in vivo

Advanced prostate cancer has a poor prognosis, and it is urgent to develop new effective drugs. 5′-Epiequisetin is a tetramic acid derivative which was isolated from a marine sponge-derived fungus Fusarium equiseti in our previous study. In this study, 5′-epiequisetin showed cytotoxicity against fou...

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Bibliographic Details
Main Authors: Xueni Wang, Xiaowei Luo, Xia Gan, Chunmei Chen, Zaizhun Yang, Jing Wen, Wenxuan Fang, Hailing Huang, Chenghai Gao, Xuefeng Zhou, Xiaotao Feng, Yonghong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
5′-epiequisetin
prostate cancer
phosphoinositol 3-kinase
protein kinase B
death receptor 5
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.920554/full

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