Inhibitory Effect of Piceatannol on Streptococcus suis Infection Both in vitro and in vivo

Inhibitory Effect of Piceatannol on Streptococcus suis Infection Both in vitro and in vivo

Suilysin (SLY) plays a critical role in Streptococcus suis infections making it an ideal target to the combat infection caused by this pathogen. In the present study, we found that piceatannol (PN), a natural compound, inhibits pore-formation by blocking the oligomerization of SLY without affecting...

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Bibliographic Details
Main Authors: Guizhen Wang, Yawen Gao, Xiuhua Wu, Xiue Gao, Min Zhang, Hongmei Liu, Tianqi Fang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Microbiology
Subjects:
Streptococcus suis
piceatannol
suilysin
virulence
molecular modeling
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2020.593588/full

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