Potential value of ctDNA monitoring in metastatic HR + /HER2 − breast cancer: longitudinal ctDNA analysis in the phase Ib MONALEESASIA trial

Potential value of ctDNA monitoring in metastatic HR + /HER2 − breast cancer: longitudinal ctDNA analysis in the phase Ib MONALEESASIA trial

Abstract Background There is increasing interest in the use of liquid biopsies, but data on longitudinal analyses of circulating tumor DNA (ctDNA) remain relatively limited. Here, we report a longitudinal ctDNA analysis of MONALEESASIA, a phase Ib trial evaluating the efficacy and safety of ribocicl...

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Bibliographic Details
Main Authors: Joanne Chiu, Fei Su, Mukta Joshi, Norikazu Masuda, Takashi Ishikawa, Tomoyuki Aruga, Juan Pablo Zarate, Naveen Babbar, O. Alejandro Balbin, Yoon-Sim Yap
Format: Article
Language:English
Published: BMC 2023-08-01
Series:BMC Medicine
Subjects:
Ribociclib
MONALEESASIA
Advanced breast cancer
CDK4/6 inhibitor
ctDNA
Longitudinal analysis
Online Access:https://doi.org/10.1186/s12916-023-03017-z

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