Breakthrough pain among cancer patients at oncology units in Northern Ethiopia; a multi-center study
BackgroundBreakthrough cancer pain (BTCP) is a transient exacerbation of pain that affects the length of hospitalization and quality of life of patients. The objective of this study was to determine the prevalence and factors associated with BTCP among cancer patients at oncology units in Northern E...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-01-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1248921/full |
| _version_ | 1797360311193305088 |
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| author | Yohanes Tekie Yonas Addisu Nigatu Wudie Mekonnen Yophtahe Woldegerima Berhe |
| author_facet | Yohanes Tekie Yonas Addisu Nigatu Wudie Mekonnen Yophtahe Woldegerima Berhe |
| author_sort | Yohanes Tekie |
| collection | DOAJ |
| description | BackgroundBreakthrough cancer pain (BTCP) is a transient exacerbation of pain that affects the length of hospitalization and quality of life of patients. The objective of this study was to determine the prevalence and factors associated with BTCP among cancer patients at oncology units in Northern Ethiopia in 2022.MethodsA multi-center cross-sectional study was conducted from April to June 2022. After obtaining ethical approval, data were collected prospectively from 424 adult cancer patients admitted to oncology units. Breakthrough cancer pain was assessed by the numeric rating scale. Descriptive and binary logistic regression analyses were performed to determine the factors associated with BTCP. The strength of association was described in adjusted odds ratio (AOR) with 95% confidence intervals and variables with a P-value < 0.05 were considered to have a statistically significant association with BTCP.ResultThe prevalence of BTCP among cancer patients was 41.5%. The factors that were found to be associated with BTCP were colorectal cancer (AOR: 7.7, 95% CI: 1.8, 32.3), lung cancer (AOR: 6.9, 95% CI: 1.9, 26.0), metastasis (AOR: 9.3, 95% CI: 3.0, 29.1), mild background pain (AOR: 7.5, 95% CI: 2.5, 22.6), moderate background pain (AOR: 7.0, 95% CI: 2.2, 23.1), severe background pain (AOR: 7.1, 95% CI: 2.2, 22.8), no analgesics taken for background pain (AOR: 5.1, 95% CI: 2.8, 9.3) and uncontrolled background pain (AOR: 3.3, 95% CI: 1.8, 6.1).ConclusionThe prevalence of BTCP was high. Colorectal cancer, lung cancer, the presence of metastasis, the presence of background pain, not taking analgesics for background pain, and uncontrolled background pain were significantly associated with BTCP. |
| first_indexed | 2024-03-08T15:36:29Z |
| format | Article |
| id | doaj.art-5e8d59daab47403994c307a9bc63af32 |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-03-08T15:36:29Z |
| publishDate | 2024-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-5e8d59daab47403994c307a9bc63af322024-01-09T18:28:25ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2024-01-011310.3389/fonc.2023.12489211248921Breakthrough pain among cancer patients at oncology units in Northern Ethiopia; a multi-center studyYohanes Tekie0Yonas Addisu Nigatu1Wudie Mekonnen2Yophtahe Woldegerima Berhe3Department of Anesthesia, Aksum University, Aksum, EthiopiaDepartment of Anesthesia, University of Gondar, Gondar, EthiopiaDepartment of Anesthesia, University of Gondar, Gondar, EthiopiaDepartment of Anesthesia, University of Gondar, Gondar, EthiopiaBackgroundBreakthrough cancer pain (BTCP) is a transient exacerbation of pain that affects the length of hospitalization and quality of life of patients. The objective of this study was to determine the prevalence and factors associated with BTCP among cancer patients at oncology units in Northern Ethiopia in 2022.MethodsA multi-center cross-sectional study was conducted from April to June 2022. After obtaining ethical approval, data were collected prospectively from 424 adult cancer patients admitted to oncology units. Breakthrough cancer pain was assessed by the numeric rating scale. Descriptive and binary logistic regression analyses were performed to determine the factors associated with BTCP. The strength of association was described in adjusted odds ratio (AOR) with 95% confidence intervals and variables with a P-value < 0.05 were considered to have a statistically significant association with BTCP.ResultThe prevalence of BTCP among cancer patients was 41.5%. The factors that were found to be associated with BTCP were colorectal cancer (AOR: 7.7, 95% CI: 1.8, 32.3), lung cancer (AOR: 6.9, 95% CI: 1.9, 26.0), metastasis (AOR: 9.3, 95% CI: 3.0, 29.1), mild background pain (AOR: 7.5, 95% CI: 2.5, 22.6), moderate background pain (AOR: 7.0, 95% CI: 2.2, 23.1), severe background pain (AOR: 7.1, 95% CI: 2.2, 22.8), no analgesics taken for background pain (AOR: 5.1, 95% CI: 2.8, 9.3) and uncontrolled background pain (AOR: 3.3, 95% CI: 1.8, 6.1).ConclusionThe prevalence of BTCP was high. Colorectal cancer, lung cancer, the presence of metastasis, the presence of background pain, not taking analgesics for background pain, and uncontrolled background pain were significantly associated with BTCP.https://www.frontiersin.org/articles/10.3389/fonc.2023.1248921/fullbreakthrough paincancer paincancerpainbreakthrough cancer pain (BTCP) |
| spellingShingle | Yohanes Tekie Yonas Addisu Nigatu Wudie Mekonnen Yophtahe Woldegerima Berhe Breakthrough pain among cancer patients at oncology units in Northern Ethiopia; a multi-center study Frontiers in Oncology breakthrough pain cancer pain cancer pain breakthrough cancer pain (BTCP) |
| title | Breakthrough pain among cancer patients at oncology units in Northern Ethiopia; a multi-center study |
| title_full | Breakthrough pain among cancer patients at oncology units in Northern Ethiopia; a multi-center study |
| title_fullStr | Breakthrough pain among cancer patients at oncology units in Northern Ethiopia; a multi-center study |
| title_full_unstemmed | Breakthrough pain among cancer patients at oncology units in Northern Ethiopia; a multi-center study |
| title_short | Breakthrough pain among cancer patients at oncology units in Northern Ethiopia; a multi-center study |
| title_sort | breakthrough pain among cancer patients at oncology units in northern ethiopia a multi center study |
| topic | breakthrough pain cancer pain cancer pain breakthrough cancer pain (BTCP) |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2023.1248921/full |
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