138 Shared frameshift neoantigens are expressed throughout mismatch repair deficient cancer development and are recognized by tissue infiltrating T cells that are dysregulated in advanced lesions

Bibliographic Details
Main Authors: Matthew Brown, Nina Bhardwaj, Cansu Cimen Bozkus, Aimee L Lucas, Alexandros D Polydorides, Leandra Velazquez, Mesude Bicak, Juhana Habib, Sharonne Holtzman, Mona Saleh, Robert Samstein
Format: Article
Language:English
Published: BMJ Publishing Group 2023-11-01
Series:Journal for ImmunoTherapy of Cancer
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author Matthew Brown
Nina Bhardwaj
Cansu Cimen Bozkus
Aimee L Lucas
Alexandros D Polydorides
Leandra Velazquez
Mesude Bicak
Juhana Habib
Sharonne Holtzman
Mona Saleh
Robert Samstein
author_facet Matthew Brown
Nina Bhardwaj
Cansu Cimen Bozkus
Aimee L Lucas
Alexandros D Polydorides
Leandra Velazquez
Mesude Bicak
Juhana Habib
Sharonne Holtzman
Mona Saleh
Robert Samstein
author_sort Matthew Brown
collection DOAJ
first_indexed 2024-03-08T21:34:08Z
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institution Directory Open Access Journal
issn 2051-1426
language English
last_indexed 2024-03-08T21:34:08Z
publishDate 2023-11-01
publisher BMJ Publishing Group
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series Journal for ImmunoTherapy of Cancer
spelling doaj.art-5e8efdbf4f6643c9a5698a410d60bd9c2023-12-21T02:10:09ZengBMJ Publishing GroupJournal for ImmunoTherapy of Cancer2051-14262023-11-0111Suppl 110.1136/jitc-2023-SITC2023.0138138 Shared frameshift neoantigens are expressed throughout mismatch repair deficient cancer development and are recognized by tissue infiltrating T cells that are dysregulated in advanced lesionsMatthew Brown0Nina Bhardwaj1Cansu Cimen Bozkus2Aimee L Lucas3Alexandros D Polydorides4Leandra Velazquez5Mesude Bicak6Juhana Habib7Sharonne Holtzman8Mona Saleh9Robert Samstein101Icahn School of Medicine at Mount Sinai, New York, NY, USA3Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA3Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA1Icahn School of Medicine at Mount Sinai, New York, NY, USA5Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, NY, USA3Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA3Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA2Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA4Department of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA4Department of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA7Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA
spellingShingle Matthew Brown
Nina Bhardwaj
Cansu Cimen Bozkus
Aimee L Lucas
Alexandros D Polydorides
Leandra Velazquez
Mesude Bicak
Juhana Habib
Sharonne Holtzman
Mona Saleh
Robert Samstein
138 Shared frameshift neoantigens are expressed throughout mismatch repair deficient cancer development and are recognized by tissue infiltrating T cells that are dysregulated in advanced lesions
Journal for ImmunoTherapy of Cancer
title 138 Shared frameshift neoantigens are expressed throughout mismatch repair deficient cancer development and are recognized by tissue infiltrating T cells that are dysregulated in advanced lesions
title_full 138 Shared frameshift neoantigens are expressed throughout mismatch repair deficient cancer development and are recognized by tissue infiltrating T cells that are dysregulated in advanced lesions
title_fullStr 138 Shared frameshift neoantigens are expressed throughout mismatch repair deficient cancer development and are recognized by tissue infiltrating T cells that are dysregulated in advanced lesions
title_full_unstemmed 138 Shared frameshift neoantigens are expressed throughout mismatch repair deficient cancer development and are recognized by tissue infiltrating T cells that are dysregulated in advanced lesions
title_short 138 Shared frameshift neoantigens are expressed throughout mismatch repair deficient cancer development and are recognized by tissue infiltrating T cells that are dysregulated in advanced lesions
title_sort 138 shared frameshift neoantigens are expressed throughout mismatch repair deficient cancer development and are recognized by tissue infiltrating t cells that are dysregulated in advanced lesions
work_keys_str_mv AT matthewbrown 138sharedframeshiftneoantigensareexpressedthroughoutmismatchrepairdeficientcancerdevelopmentandarerecognizedbytissueinfiltratingtcellsthataredysregulatedinadvancedlesions
AT ninabhardwaj 138sharedframeshiftneoantigensareexpressedthroughoutmismatchrepairdeficientcancerdevelopmentandarerecognizedbytissueinfiltratingtcellsthataredysregulatedinadvancedlesions
AT cansucimenbozkus 138sharedframeshiftneoantigensareexpressedthroughoutmismatchrepairdeficientcancerdevelopmentandarerecognizedbytissueinfiltratingtcellsthataredysregulatedinadvancedlesions
AT aimeellucas 138sharedframeshiftneoantigensareexpressedthroughoutmismatchrepairdeficientcancerdevelopmentandarerecognizedbytissueinfiltratingtcellsthataredysregulatedinadvancedlesions
AT alexandrosdpolydorides 138sharedframeshiftneoantigensareexpressedthroughoutmismatchrepairdeficientcancerdevelopmentandarerecognizedbytissueinfiltratingtcellsthataredysregulatedinadvancedlesions
AT leandravelazquez 138sharedframeshiftneoantigensareexpressedthroughoutmismatchrepairdeficientcancerdevelopmentandarerecognizedbytissueinfiltratingtcellsthataredysregulatedinadvancedlesions
AT mesudebicak 138sharedframeshiftneoantigensareexpressedthroughoutmismatchrepairdeficientcancerdevelopmentandarerecognizedbytissueinfiltratingtcellsthataredysregulatedinadvancedlesions
AT juhanahabib 138sharedframeshiftneoantigensareexpressedthroughoutmismatchrepairdeficientcancerdevelopmentandarerecognizedbytissueinfiltratingtcellsthataredysregulatedinadvancedlesions
AT sharonneholtzman 138sharedframeshiftneoantigensareexpressedthroughoutmismatchrepairdeficientcancerdevelopmentandarerecognizedbytissueinfiltratingtcellsthataredysregulatedinadvancedlesions
AT monasaleh 138sharedframeshiftneoantigensareexpressedthroughoutmismatchrepairdeficientcancerdevelopmentandarerecognizedbytissueinfiltratingtcellsthataredysregulatedinadvancedlesions
AT robertsamstein 138sharedframeshiftneoantigensareexpressedthroughoutmismatchrepairdeficientcancerdevelopmentandarerecognizedbytissueinfiltratingtcellsthataredysregulatedinadvancedlesions