Access to direct-acting antivirals for the treatment of hepatitis C in a country with limited resources
Aims: To estimate the number of patients that have access to treatment of hepatitis C with direct-acting antivirals in Argentina and evaluate the factors associated with the lack of access. Materials and methods: A cross-sectional cohort study was conducted that included all the consecutive prescrip...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2018-04-01
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| Series: | Revista de Gastroenterología de México (English Edition) |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2255534X18300616 |
| _version_ | 1818265626537361408 |
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| author | S. Marciano L. Haddad S.M. Borzi C. D’Amico L.A. Gaite M.V. Aubone M.E. Sirotinsky N. Ratusnu M.S. Frola M.C. Aparicio B. Ríos M.N. Anselmo R. Hansen S. De Filippi C. García Dans L. de Labra M.A. Peche T.M. Strella M. Ibáñez Duran M.B. García Rosales M. Dirchwolf O.A. Galdame A.C. Gadano |
| author_facet | S. Marciano L. Haddad S.M. Borzi C. D’Amico L.A. Gaite M.V. Aubone M.E. Sirotinsky N. Ratusnu M.S. Frola M.C. Aparicio B. Ríos M.N. Anselmo R. Hansen S. De Filippi C. García Dans L. de Labra M.A. Peche T.M. Strella M. Ibáñez Duran M.B. García Rosales M. Dirchwolf O.A. Galdame A.C. Gadano |
| author_sort | S. Marciano |
| collection | DOAJ |
| description | Aims: To estimate the number of patients that have access to treatment of hepatitis C with direct-acting antivirals in Argentina and evaluate the factors associated with the lack of access. Materials and methods: A cross-sectional cohort study was conducted that included all the consecutive prescriptions of direct-acting antivirals issued at health centers that participated in the ECHOTM telemedicine project directed by the Hospital Italiano de Buenos Aires, within the time frame of January 2016 and February 2017. Results: A total of 143 treatment prescriptions were included and overall access was 70% (95% CI 62-77%). The only independent factor associated with a lack of treatment access was coverage by a public healthcare system (OR 4.98 [95% CI 2.05- 12.09]). Conclusions: Patients with hepatitis C that were covered by a public healthcare system had a 4 times higher chance of not having access to treatment with direct-acting antivirals than patients covered by other healthcare systems (private insurance or the social welfare system). Resumen: Objetivos: Estimar la proporción de pacientes que acceden al tratamiento de la hepatitis C con antivirales de acción directa (AAD) en Argentina, y evaluar factores asociados a la falta de acceso. Métodos: Estudio de cohorte transversal que incluyó la totalidad de prescripciones consecutivas de AAD realizadas entre enero de 2016 y febrero de 2017 por centros de salud que participan en el proyecto de telemedicina ECHOTM dirigido por el Hospital Italiano de Buenos Aires. Resultados: Se incluyeron 143 prescripciones de tratamiento. El acceso global fue del 70% (IC95%: 62-77%). Pertenecer al sistema de salud público fue el único factor independiente asociado con la falta de acceso al tratamiento [OR 4.98 (IC95% 2.05-12.09)]. Conclusión: Los pacientes con hepatitis C pertenecientes al sistema de salud público tienen 4 veces más chances de no acceder a tratamiento con AAD que los pacientes con dependencia de otros sistemas de salud (medicina privada u obras sociales). Keywords: Direct-acting antivirals, Access, Hepatitis C, Healthcare systems, Barriers, Palabras clave: Antivirales de acción directa, Acceso, Hepatitis C, Sistemas de salud, Barreras |
| first_indexed | 2024-12-12T19:53:48Z |
| format | Article |
| id | doaj.art-5e90b9cf677f4ef092eaaebdf6883d3c |
| institution | Directory Open Access Journal |
| issn | 2255-534X |
| language | English |
| last_indexed | 2024-12-12T19:53:48Z |
| publishDate | 2018-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Revista de Gastroenterología de México (English Edition) |
| spelling | doaj.art-5e90b9cf677f4ef092eaaebdf6883d3c2022-12-22T00:13:56ZengElsevierRevista de Gastroenterología de México (English Edition)2255-534X2018-04-01832208211Access to direct-acting antivirals for the treatment of hepatitis C in a country with limited resourcesS. Marciano0L. Haddad1S.M. Borzi2C. D’Amico3L.A. Gaite4M.V. Aubone5M.E. Sirotinsky6N. Ratusnu7M.S. Frola8M.C. Aparicio9B. Ríos10M.N. Anselmo11R. Hansen12S. De Filippi13C. García Dans14L. de Labra15M.A. Peche16T.M. Strella17M. Ibáñez Duran18M.B. García Rosales19M. Dirchwolf20O.A. Galdame21A.C. Gadano22Sección de Hepatología, Hospital Italiano, Buenos Aires, Argentina; Departamento de Investigación, Hospital Italiano, Buenos Aires, Argentina; Corresponding author.Sección de Hepatología y Departamento de Investigación, Hospital Italiano de Buenos Aires. Dirección: Juan Domingo Perón 4190 - CP: 1181ACH, Ciudad Autónoma de Buenos Aires, Argentina. Phone: +54-11-49590200-5370, fax: +54-11-49590346.Sección de Hepatología, Hospital Italiano, Buenos Aires, ArgentinaSección de Hepatología, Hospital R. Rossi, La Plata, Buenos Aires, ArgentinaHepatología, Centro de Especialidades Médicas Ambulatorias (CEMA), Municipalidad General Pueyrredón, Mar del Plata, ArgentinaUnidad de Hepatología y Trasplante Hepático, Clínica de Nefrología, Santa Fe, ArgentinaSección de Hepatología, Hospital R. Rossi, La Plata, Buenos Aires, ArgentinaCentro de Estudios Digestivos (CEDIG), Comodoro Rivadavia, Chubut, ArgentinaHospital Regional de Ushuaia, Ushuaia, Tierra del Fuego, ArgentinaServicio de Infectología, Hospital Luis Pasteur, Villa María, Córdoba, ArgentinaHospital Artemides Zatti, Viedma, Río Negro, ArgentinaSección de Infectología, Centro de Investigación (CEIN), Neuquén, ArgentinaServicio de Gastroenterología y Hepatología, Hospital Zonal Esquel, Esquel, Chubut, ArgentinaHospital de Área El Bolsón, El Bolsón, Río Negro, ArgentinaHospital Ramón Carrillo, Centro Médico del Sur, San Martín de los Andes, Neuquén, ArgentinaHospital Zonal Bariloche Dr. Ramón Carrillo, Bariloche, Río Negro, ArgentinaHospital Zonal Bariloche Dr. Ramón Carrillo, Bariloche, Río Negro, ArgentinaHospital Francisco López Lima, General Roca, Río Negro, ArgentinaHospital Zonal Puerto Madryn Dr. Andrés Ísola, Puerto Madryn, Chubut, ArgentinaHospital Zatti, Viedma, Río Negro, ArgentinaHepatología y Gastroenterología, Centro de Estudios Digestivos de Mendoza (CEDIM), Mendoza, ArgentinaUnidad de Hígado, Hospital Privado de Rosario, Rosario, Santa Fe, ArgentinaSección de Hepatología, Hospital Italiano, Buenos Aires, ArgentinaSección de Hepatología, Hospital Italiano, Buenos Aires, Argentina; Departamento de Investigación, Hospital Italiano, Buenos Aires, ArgentinaAims: To estimate the number of patients that have access to treatment of hepatitis C with direct-acting antivirals in Argentina and evaluate the factors associated with the lack of access. Materials and methods: A cross-sectional cohort study was conducted that included all the consecutive prescriptions of direct-acting antivirals issued at health centers that participated in the ECHOTM telemedicine project directed by the Hospital Italiano de Buenos Aires, within the time frame of January 2016 and February 2017. Results: A total of 143 treatment prescriptions were included and overall access was 70% (95% CI 62-77%). The only independent factor associated with a lack of treatment access was coverage by a public healthcare system (OR 4.98 [95% CI 2.05- 12.09]). Conclusions: Patients with hepatitis C that were covered by a public healthcare system had a 4 times higher chance of not having access to treatment with direct-acting antivirals than patients covered by other healthcare systems (private insurance or the social welfare system). Resumen: Objetivos: Estimar la proporción de pacientes que acceden al tratamiento de la hepatitis C con antivirales de acción directa (AAD) en Argentina, y evaluar factores asociados a la falta de acceso. Métodos: Estudio de cohorte transversal que incluyó la totalidad de prescripciones consecutivas de AAD realizadas entre enero de 2016 y febrero de 2017 por centros de salud que participan en el proyecto de telemedicina ECHOTM dirigido por el Hospital Italiano de Buenos Aires. Resultados: Se incluyeron 143 prescripciones de tratamiento. El acceso global fue del 70% (IC95%: 62-77%). Pertenecer al sistema de salud público fue el único factor independiente asociado con la falta de acceso al tratamiento [OR 4.98 (IC95% 2.05-12.09)]. Conclusión: Los pacientes con hepatitis C pertenecientes al sistema de salud público tienen 4 veces más chances de no acceder a tratamiento con AAD que los pacientes con dependencia de otros sistemas de salud (medicina privada u obras sociales). Keywords: Direct-acting antivirals, Access, Hepatitis C, Healthcare systems, Barriers, Palabras clave: Antivirales de acción directa, Acceso, Hepatitis C, Sistemas de salud, Barrerashttp://www.sciencedirect.com/science/article/pii/S2255534X18300616 |
| spellingShingle | S. Marciano L. Haddad S.M. Borzi C. D’Amico L.A. Gaite M.V. Aubone M.E. Sirotinsky N. Ratusnu M.S. Frola M.C. Aparicio B. Ríos M.N. Anselmo R. Hansen S. De Filippi C. García Dans L. de Labra M.A. Peche T.M. Strella M. Ibáñez Duran M.B. García Rosales M. Dirchwolf O.A. Galdame A.C. Gadano Access to direct-acting antivirals for the treatment of hepatitis C in a country with limited resources Revista de Gastroenterología de México (English Edition) |
| title | Access to direct-acting antivirals for the treatment of hepatitis C in a country with limited resources |
| title_full | Access to direct-acting antivirals for the treatment of hepatitis C in a country with limited resources |
| title_fullStr | Access to direct-acting antivirals for the treatment of hepatitis C in a country with limited resources |
| title_full_unstemmed | Access to direct-acting antivirals for the treatment of hepatitis C in a country with limited resources |
| title_short | Access to direct-acting antivirals for the treatment of hepatitis C in a country with limited resources |
| title_sort | access to direct acting antivirals for the treatment of hepatitis c in a country with limited resources |
| url | http://www.sciencedirect.com/science/article/pii/S2255534X18300616 |
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