NELA Risk Calculator Significantly Underestimates Mortality Risk of Laparotomy for Mesenteric and Colonic Ischaemia in Older Adult Surgical Patients

Louis Connell Acute Surgical Unit, Sir Charles Gairdner Hospital, Perth, Western Australia, AustraliaCorrespondence: Louis Connell, Email louisconnell277@gmail.comAim: To establish if the NELA risk calculator underestimates mortality risk in older adults undergoing laparotomy for mesenteric or colon...

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Bibliographic Details
Main Author: Connell L
Format: Article
Language:English
Published: Dove Medical Press 2023-03-01
Series:Open Access Surgery
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Online Access:https://www.dovepress.com/nela-risk-calculator-significantly-underestimates-mortality-risk-of-la-peer-reviewed-fulltext-article-OAS
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Summary:Louis Connell Acute Surgical Unit, Sir Charles Gairdner Hospital, Perth, Western Australia, AustraliaCorrespondence: Louis Connell, Email louisconnell277@gmail.comAim: To establish if the NELA risk calculator underestimates mortality risk in older adults undergoing laparotomy for mesenteric or colonic ischaemia.Methods: A retrospective search of the operative database was performed for all patients over age 65 years who underwent laparotomy across two tertiary centres over a 3-year period. Cases of mesenteric or colonic ischaemia were identified from the operative records. Cases where ischaemia occurred secondarily to a primary obstructive or other pathology were excluded. Cases where a NELA score was not documented preoperatively were excluded. We then compared the NELA scores to the observed 30-day mortality rate. Secondary outcomes were hospital length of stay and intensive care unit length of stay.Results: Sixty cases were included in our analysis. There were 27 cases of colonic ischaemia and 33 cases of mesenteric ischaemia (mesenteric ischaemia group included five cases of distal small-bowel and colonic ischaemia). The overall mean NELA score was 21.9%, while the actual 30-day mortality was 43.3% (p=0.0094). Mean NELA score for mesenteric ischaemia cases only was 20.6% with an actual mortality rate of 45.5%. Mean NELA score for the colonic ischaemia cases was 23.5% with an actual mortality rate of 40.7%. The median time from operation to mortality was 8 days. Mean age was 77 years. Length of stay for survivors was a mean 27 days with intensive care unit length of stay of 9.3 days.Conclusion: The NELA risk score for mortality post–emergency laparotomy underestimates mortality risk by a factor of two in older adults where the primary pathology is mesenteric or colonic ischaemia.Keywords: mesenteric, ischaemia, colonic, NELA, mortality
ISSN:1178-7082